Synchronous local recurrence and liver metastasis from extragastrointestinal stromal tumor in the rectovaginal septum: a unique case presentation
The rectovaginal septum is a rare location for gastrointestinal stromal tumors (GIST) to occur. The aim of this study was to present a case of synchronous local recurrence of solitary liver metastasis originating from an extra gastrointestinal tumor (E-GIST) of the rectovaginal space. A 55-year-...
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| Format: | Article |
| Language: | English |
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Pensoft Publishers
2024-12-01
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| Series: | Folia Medica |
| Online Access: | https://foliamedica.bg/article/125700/download/pdf/ |
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| author | Eleni Papamattheou Ioannis Katsaros Eirini Chorianopoulou Kyriaki Theodorolea Gabriela Stanc Christos Iavazzo Elissaios Kontis |
| author_facet | Eleni Papamattheou Ioannis Katsaros Eirini Chorianopoulou Kyriaki Theodorolea Gabriela Stanc Christos Iavazzo Elissaios Kontis |
| author_sort | Eleni Papamattheou |
| collection | DOAJ |
| description | The rectovaginal septum is a rare location for gastrointestinal stromal tumors (GIST) to occur. The aim of this study was to present a case of synchronous local recurrence of solitary liver metastasis originating from an extra gastrointestinal tumor (E-GIST) of the rectovaginal space. A 55-year-old woman, with a medical history of a resected meningioma, was referred to our department due to a 5 cm solitary liver metastasis located within the left lateral segment. The patient had undergone a transvaginal resection of a low-risk E-GIST 6 months prior without receiving adjuvant chemotherapy. The patient underwent a synchronous laparoscopic left lateral hepatectomy and a transvaginal resection with posterior vaginal wall reconstruction. Her postoperative course was uneventful and was discharged on the fifth postoperative day. The histological examination of the vaginal lesion revealed the development of neoplasm with pathological characteristics consistent with the initial histology expect for a mitotic index exceeding >20%. Liver histology report also included a high-risk GIST with CKIT (+), DOG1 (+), ki67 ≥30%, high mitotic activity and clear resection margins. The patient was referred for adjuvant chemotherapy. E-GISTs are rare neoplasms with low malignant potential. However, these tumors may exhibit metastatic potential and require aggressive treatment. |
| format | Article |
| id | doaj-art-9fc4e1a95a8c4cfb8b18bd51c972139e |
| institution | Kabale University |
| issn | 1314-2143 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Pensoft Publishers |
| record_format | Article |
| series | Folia Medica |
| spelling | doaj-art-9fc4e1a95a8c4cfb8b18bd51c972139e2025-01-07T08:30:14ZengPensoft PublishersFolia Medica1314-21432024-12-0166692392810.3897/folmed.66.e125700125700Synchronous local recurrence and liver metastasis from extragastrointestinal stromal tumor in the rectovaginal septum: a unique case presentationEleni Papamattheou0Ioannis Katsaros1Eirini Chorianopoulou2Kyriaki Theodorolea3Gabriela Stanc4Christos Iavazzo5Elissaios Kontis6Metaxa Cancer HospitalMetaxa Cancer HospitalMetaxa Cancer HospitalMetaxa Cancer HospitalMetaxa Cancer HospitalMetaxa Cancer HospitalMetaxa Cancer HospitalThe rectovaginal septum is a rare location for gastrointestinal stromal tumors (GIST) to occur. The aim of this study was to present a case of synchronous local recurrence of solitary liver metastasis originating from an extra gastrointestinal tumor (E-GIST) of the rectovaginal space. A 55-year-old woman, with a medical history of a resected meningioma, was referred to our department due to a 5 cm solitary liver metastasis located within the left lateral segment. The patient had undergone a transvaginal resection of a low-risk E-GIST 6 months prior without receiving adjuvant chemotherapy. The patient underwent a synchronous laparoscopic left lateral hepatectomy and a transvaginal resection with posterior vaginal wall reconstruction. Her postoperative course was uneventful and was discharged on the fifth postoperative day. The histological examination of the vaginal lesion revealed the development of neoplasm with pathological characteristics consistent with the initial histology expect for a mitotic index exceeding >20%. Liver histology report also included a high-risk GIST with CKIT (+), DOG1 (+), ki67 ≥30%, high mitotic activity and clear resection margins. The patient was referred for adjuvant chemotherapy. E-GISTs are rare neoplasms with low malignant potential. However, these tumors may exhibit metastatic potential and require aggressive treatment.https://foliamedica.bg/article/125700/download/pdf/ |
| spellingShingle | Eleni Papamattheou Ioannis Katsaros Eirini Chorianopoulou Kyriaki Theodorolea Gabriela Stanc Christos Iavazzo Elissaios Kontis Synchronous local recurrence and liver metastasis from extragastrointestinal stromal tumor in the rectovaginal septum: a unique case presentation Folia Medica |
| title | Synchronous local recurrence and liver metastasis from extragastrointestinal stromal tumor in the rectovaginal septum: a unique case presentation |
| title_full | Synchronous local recurrence and liver metastasis from extragastrointestinal stromal tumor in the rectovaginal septum: a unique case presentation |
| title_fullStr | Synchronous local recurrence and liver metastasis from extragastrointestinal stromal tumor in the rectovaginal septum: a unique case presentation |
| title_full_unstemmed | Synchronous local recurrence and liver metastasis from extragastrointestinal stromal tumor in the rectovaginal septum: a unique case presentation |
| title_short | Synchronous local recurrence and liver metastasis from extragastrointestinal stromal tumor in the rectovaginal septum: a unique case presentation |
| title_sort | synchronous local recurrence and liver metastasis from extragastrointestinal stromal tumor in the rectovaginal septum a unique case presentation |
| url | https://foliamedica.bg/article/125700/download/pdf/ |
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