Enhancing T-cell recruitment in renal cell carcinoma with cytokine-armed adenoviruses

Enhancing T-cell recruitment in renal cell carcinoma with cytokine-armed adenoviruses

Immunotherapy has emerged as a promising approach for cancer treatment, with oncolytic adenoviruses showing power as immunotherapeutic agents. In this study, we investigated the immunotherapeutic potential of an adenovirus construct expressing CXCL9, CXCL10, or IL-15 in clear cell renal cell carcino...

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Main Authors: Michaela Feodoroff, Firas Hamdan, Gabriella Antignani, Sara Feola, Manlio Fusciello, Salvatore Russo, Jacopo Chiaro, Katja Välimäki, Teijo Pellinen, Rui M. Branca, Janne Lehtiö, Federica D´alessio, Paolo Bottega, Virpi Stigzelius, Janita Sandberg, Jonna Clancy, Jukka Partanen, Minna Malmstedt, Antti Rannikko, Vilja Pietiäinen, Mikaela Grönholm, Vincenzo Cerullo
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:OncoImmunology
Subjects:
Cytokines
immunotherapy
oncolytic viruses
renal cell carcinoma
tumor peptides
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2024.2407532
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