Current research on determination of medically valued stilbenes and stilbenoids from spruce and pine with chromatographic and spectrometric methods—A review

The review compiles a selection of the recently published chemical research on stilbenes, stilbene glucuronides, and stilbenoids. The basic structure of stilbene group compounds is 1,2-diphenylethene. They can be isolated from spruce, pine, and other conifers, and specifically from wood bark, needle...

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Main Author: Heli Sirén
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Journal of Chromatography Open
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Online Access:http://www.sciencedirect.com/science/article/pii/S2772391724000562
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author Heli Sirén
author_facet Heli Sirén
author_sort Heli Sirén
collection DOAJ
description The review compiles a selection of the recently published chemical research on stilbenes, stilbene glucuronides, and stilbenoids. The basic structure of stilbene group compounds is 1,2-diphenylethene. They can be isolated from spruce, pine, and other conifers, and specifically from wood bark, needles, heartwood, and roots.Stilbenes and stilbenoids possess antioxidative, anti-inflammatory, and antimicrobial impacts what for they are used in pharmaceuticals. They decrease of glucose and triglyceride concentrations in plasma. Especially, they are used for treatment of cancer, liver injuries, and Alzheimer's disease.Lately, extraction of stilbene group compounds from wood materials was done with alcohol, water, or nonpolar solvents. Moreover, they were extracted with supercritical fluid and hot water extraction methods. Rectified extracts were studied with liquid and/or gas chromatography. Mass spectrometry with negative electrospray ionization was the prevalent method for their identification. HPLC-MS methods were preferred over GC to identify dimeric stilbenes and oligomeric stilbenoids.
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spelling doaj-art-9f62985cb32f4a0b926e1bbd072f45942024-12-14T06:34:09ZengElsevierJournal of Chromatography Open2772-39172024-11-016100169Current research on determination of medically valued stilbenes and stilbenoids from spruce and pine with chromatographic and spectrometric methods—A reviewHeli Sirén0Department of Chemistry, University of Helsinki, A.I. Virtasen aukio 1, FI 00560, Helsinki, FinlandThe review compiles a selection of the recently published chemical research on stilbenes, stilbene glucuronides, and stilbenoids. The basic structure of stilbene group compounds is 1,2-diphenylethene. They can be isolated from spruce, pine, and other conifers, and specifically from wood bark, needles, heartwood, and roots.Stilbenes and stilbenoids possess antioxidative, anti-inflammatory, and antimicrobial impacts what for they are used in pharmaceuticals. They decrease of glucose and triglyceride concentrations in plasma. Especially, they are used for treatment of cancer, liver injuries, and Alzheimer's disease.Lately, extraction of stilbene group compounds from wood materials was done with alcohol, water, or nonpolar solvents. Moreover, they were extracted with supercritical fluid and hot water extraction methods. Rectified extracts were studied with liquid and/or gas chromatography. Mass spectrometry with negative electrospray ionization was the prevalent method for their identification. HPLC-MS methods were preferred over GC to identify dimeric stilbenes and oligomeric stilbenoids.http://www.sciencedirect.com/science/article/pii/S2772391724000562Stilbenes and stilbenoidsWood speciesIsolationChromatographyMass spectrometryDiseases
spellingShingle Heli Sirén
Current research on determination of medically valued stilbenes and stilbenoids from spruce and pine with chromatographic and spectrometric methods—A review
Journal of Chromatography Open
Stilbenes and stilbenoids
Wood species
Isolation
Chromatography
Mass spectrometry
Diseases
title Current research on determination of medically valued stilbenes and stilbenoids from spruce and pine with chromatographic and spectrometric methods—A review
title_full Current research on determination of medically valued stilbenes and stilbenoids from spruce and pine with chromatographic and spectrometric methods—A review
title_fullStr Current research on determination of medically valued stilbenes and stilbenoids from spruce and pine with chromatographic and spectrometric methods—A review
title_full_unstemmed Current research on determination of medically valued stilbenes and stilbenoids from spruce and pine with chromatographic and spectrometric methods—A review
title_short Current research on determination of medically valued stilbenes and stilbenoids from spruce and pine with chromatographic and spectrometric methods—A review
title_sort current research on determination of medically valued stilbenes and stilbenoids from spruce and pine with chromatographic and spectrometric methods a review
topic Stilbenes and stilbenoids
Wood species
Isolation
Chromatography
Mass spectrometry
Diseases
url http://www.sciencedirect.com/science/article/pii/S2772391724000562
work_keys_str_mv AT helisiren currentresearchondeterminationofmedicallyvaluedstilbenesandstilbenoidsfromspruceandpinewithchromatographicandspectrometricmethodsareview