High-affinity promotor binding of YhaJ mediates a low signal leakage for effective DNT detection

High-affinity promotor binding of YhaJ mediates a low signal leakage for effective DNT detection

The YhaJ transcription factor responds to dinitrophenol (DNT) and its metabolic products. The YhaJ-involving cells have been exploited for whole-cell biosensors of soil-buried landmines. Such biosensors would decrease the damage to personnel who approach landmine fields. By the structure determinati...

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Bibliographic Details
Main Authors: Myeongbin Kim, Ryun Kang, Hye Min Park, Eun Bi Cho, Hye Rim Lee, Seong Eon Ryu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Microbiology
Subjects:
YhaJ-DBD
DNT detection
low-signal-leakage
crystal structure
biosensor
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1510655/full
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