The 3D theory of osseointegration: material, topography, and time as interdependent determinants of bone–implant integration

Abstract Despite widespread clinical success of dental implants, several fundamental questions remain unresolved: How does osseointegration—a biological phenomenon distinct from conventional bone healing—actually occur? Why does bone–implant contact never reach 100%? Why has there been minimal innov...

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Bibliographic Details
Main Authors: Takahiro Ogawa, Makoto Hirota, Rune Shibata, Takanori Matsuura, Keiji Komatsu, Juri Saruta, Wael Att
Format: Article
Language:English
Published: SpringerOpen 2025-08-01
Series:International Journal of Implant Dentistry
Online Access:https://doi.org/10.1186/s40729-025-00639-1
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