Ultra-inert lanthanide chelates as mass tags for multiplexed bioanalysis

Ultra-inert lanthanide chelates as mass tags for multiplexed bioanalysis

Abstract Coordination compounds of lanthanides are indispensable in biomedical applications as MRI contrast agents and radiotherapeutics. However, since the introduction of the chelator DOTA four decades ago, there has been only limited progress on improving their thermodynamic stability and kinetic...

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Main Authors: Tomáš David, Miroslava Šedinová, Aneta Myšková, Jaroslav Kuneš, Lenka Maletínská, Radek Pohl, Martin Dračínský, Helena Mertlíková-Kaiserová, Karel Čížek, Blanka Klepetářová, Miroslava Litecká, Antonín Kaňa, David Sýkora, Adam Jaroš, Michal Straka, Miloslav Polasek
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-53867-1
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https://doi.org/10.1038/s41467-024-53867-1

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