Emerging frontiers in epigenetic-targeted therapeutics for pediatric neuroblastoma

Emerging frontiers in epigenetic-targeted therapeutics for pediatric neuroblastoma

Neuroblastoma (NB), the most prevalent extracranial solid malignancy in children, poses significant therapeutic challenges, particularly concerning high-risk subtypes characterized by an immunologically “cold” phenotype. These tumors evade immune surveillance through mechanisms such as impaired anti...

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Bibliographic Details
Main Authors:	Xiaokang Wang, Gengrui Xu, Hongyan Ma, Xiaoyan Deng, Guiping Ma
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Immunology
Subjects:	immunologically cold small-molecule targeted agents epigenetic regulation pediatric neuroblastoma therapeutic strategies
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1637626/full
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