Development of a model system for in vitro simulated application testing of neurovascular stent systems
In vitro test setups for simulated application testing are necessary for physician training as well as for development and benchmarking of various devices in interventional neuroradiology. Within the current study, we implemented a test setup for in vitro simulated application testing. Trackability...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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De Gruyter
2024-12-01
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| Series: | Current Directions in Biomedical Engineering |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/cdbme-2024-2145 |
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| _version_ | 1846096891799928832 |
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| author | Siewert Stefan Brandt-Wunderlich Christoph Streckenbach Felix Paetow Hagen Schmidt Wolfram Stiehm Michael Langner Sönke Cantré Daniel Weber Marc-André Schmitz Klaus-Peter |
| author_facet | Siewert Stefan Brandt-Wunderlich Christoph Streckenbach Felix Paetow Hagen Schmidt Wolfram Stiehm Michael Langner Sönke Cantré Daniel Weber Marc-André Schmitz Klaus-Peter |
| author_sort | Siewert Stefan |
| collection | DOAJ |
| description | In vitro test setups for simulated application testing are necessary for physician training as well as for development and benchmarking of various devices in interventional neuroradiology. Within the current study, we implemented a test setup for in vitro simulated application testing. Trackability in the distal catheter area, which was positioned inside a complex 3D vascular model was analyzed for two neurovascular stent systems (Neuroform EZ 4.0x20 mm and Enterprise VRD 4.5x14 mm) combined with different microcatheters (Excelsior XT-27 Flex, PX Slim Delivery Microcatheter and Prowler Select Plus Infusion Catheter). The described test setup allows for a diffentiation of neurovascular stent systems with regard to the trackability force as a major procedure related indicator for device handling. Therefore, the simulated application system presented within the current work represents an indispensable tool for safely and efficiently developing and evaluating new technologies for interventional neuroradiology prior to clinical implementation. |
| format | Article |
| id | doaj-art-9ef85469a65d47649cf6648c073dc17c |
| institution | Kabale University |
| issn | 2364-5504 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Current Directions in Biomedical Engineering |
| spelling | doaj-art-9ef85469a65d47649cf6648c073dc17c2025-01-02T05:56:34ZengDe GruyterCurrent Directions in Biomedical Engineering2364-55042024-12-0110459159410.1515/cdbme-2024-2145Development of a model system for in vitro simulated application testing of neurovascular stent systemsSiewert Stefan0Brandt-Wunderlich Christoph1Streckenbach Felix2Paetow Hagen3Schmidt Wolfram4Stiehm Michael5Langner Sönke6Cantré Daniel7Weber Marc-André8Schmitz Klaus-Peter9Institute for ImplantTechnology and Biomaterials e.V., Friedrich-Barnewitz-Str. 4, 18119 Rostock-Warnemünde, GermanyInstitute for ImplantTechnology and Biomaterials e.V., Rostock-Warnemünde, GermanyRostock University Medical Center, Institute of Diagnostic and Interventional Radiology, Pediatric Radiology and Neuroradiology,Rostock, GermanyInstitute for ImplantTechnology and Biomaterials e.V., Rostock-Warnemünde, GermanyRostock University Medical Center, Institute for Biomedical Engineering, Rostock-Warnemünde, GermanyInstitute for ImplantTechnology and Biomaterials e.V., Rostock-Warnemünde, GermanyRostock University Medical Center, Institute of Diagnostic and Interventional Radiology, Pediatric Radiology and Neuroradiology,Rostock, GermanyRostock University Medical Center, Institute of Diagnostic and Interventional Radiology, Pediatric Radiology and Neuroradiology,Rostock, GermanyRostock University Medical Center, Institute of Diagnostic and Interventional Radiology, Pediatric Radiology and Neuroradiology,Rostock, GermanyInstitute for ImplantTechnology and Biomaterials e.V., Rostock-Warnemünde, GermanyIn vitro test setups for simulated application testing are necessary for physician training as well as for development and benchmarking of various devices in interventional neuroradiology. Within the current study, we implemented a test setup for in vitro simulated application testing. Trackability in the distal catheter area, which was positioned inside a complex 3D vascular model was analyzed for two neurovascular stent systems (Neuroform EZ 4.0x20 mm and Enterprise VRD 4.5x14 mm) combined with different microcatheters (Excelsior XT-27 Flex, PX Slim Delivery Microcatheter and Prowler Select Plus Infusion Catheter). The described test setup allows for a diffentiation of neurovascular stent systems with regard to the trackability force as a major procedure related indicator for device handling. Therefore, the simulated application system presented within the current work represents an indispensable tool for safely and efficiently developing and evaluating new technologies for interventional neuroradiology prior to clinical implementation.https://doi.org/10.1515/cdbme-2024-2145interventional neuroradiologysimulated usetrackability3d printed vessel model |
| spellingShingle | Siewert Stefan Brandt-Wunderlich Christoph Streckenbach Felix Paetow Hagen Schmidt Wolfram Stiehm Michael Langner Sönke Cantré Daniel Weber Marc-André Schmitz Klaus-Peter Development of a model system for in vitro simulated application testing of neurovascular stent systems Current Directions in Biomedical Engineering interventional neuroradiology simulated use trackability 3d printed vessel model |
| title | Development of a model system for in vitro simulated application testing of neurovascular stent systems |
| title_full | Development of a model system for in vitro simulated application testing of neurovascular stent systems |
| title_fullStr | Development of a model system for in vitro simulated application testing of neurovascular stent systems |
| title_full_unstemmed | Development of a model system for in vitro simulated application testing of neurovascular stent systems |
| title_short | Development of a model system for in vitro simulated application testing of neurovascular stent systems |
| title_sort | development of a model system for in vitro simulated application testing of neurovascular stent systems |
| topic | interventional neuroradiology simulated use trackability 3d printed vessel model |
| url | https://doi.org/10.1515/cdbme-2024-2145 |
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