Situational status of antibiotic resistance of E. coli in the Escalerilla WWTP, Arequipa, Peru
During the COVID-19 pandemic in Peru, a notable increase in self-medication with antibiotics has been observed, raising concerns about the increase in bacterial resistance. In this context, we evaluated the situation in wastewater treatment plants (WWTPs) using biochemical methods and sensitivity t...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Universidad de Antioquia
2024-12-01
|
| Series: | Revista Facultad de Ingeniería Universidad de Antioquia |
| Subjects: | |
| Online Access: | https://revistas.udea.edu.co/index.php/ingenieria/article/view/355727 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841526362123272192 |
|---|---|
| author | Isaac Yanqui-Morales Ricardo León-Vásquez Kusisqa Saqra Danitza DelCha Renzo Aguirre |
| author_facet | Isaac Yanqui-Morales Ricardo León-Vásquez Kusisqa Saqra Danitza DelCha Renzo Aguirre |
| author_sort | Isaac Yanqui-Morales |
| collection | DOAJ |
| description |
During the COVID-19 pandemic in Peru, a notable increase in self-medication with antibiotics has been observed, raising concerns about the increase in bacterial resistance. In this context, we evaluated the situation in wastewater treatment plants (WWTPs) using biochemical methods and sensitivity tests, such as the Kirby-Bauer assay. The results of our study show a high sensitivity to antibiotics in most of the strains analyzed, particularly towards β-lactams. However, this sensitivity appears to be influenced by seasonal patterns of medication consumption, supported by studies indicating that its contribution to the total flow is minimal. We analyzed 49 strains of Escherichia coli, 27% of which showed no resistance to any antibiotic, while the highest resistance was observed against tetracycline (63%). High levels of resistance to fluoroquinolones, such as ciprofloxacin and levofloxacin, were also recorded. In contrast, amikacin and piperacillin-tazobactam showed minimal resistance, with only one strain resistant to each. Multiresistance, defined as resistance to at least two antibiotics, was identified in 35% of the strains, with two of them showing resistance to 8 and 10 antibiotics, respectively.
|
| format | Article |
| id | doaj-art-9e89f375166d4f77a19fe5c8e6aee112 |
| institution | Kabale University |
| issn | 0120-6230 2422-2844 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Universidad de Antioquia |
| record_format | Article |
| series | Revista Facultad de Ingeniería Universidad de Antioquia |
| spelling | doaj-art-9e89f375166d4f77a19fe5c8e6aee1122025-01-17T03:43:46ZengUniversidad de AntioquiaRevista Facultad de Ingeniería Universidad de Antioquia0120-62302422-28442024-12-0110.17533/udea.redin.20241252Situational status of antibiotic resistance of E. coli in the Escalerilla WWTP, Arequipa, PeruIsaac Yanqui-Morales0Ricardo León-Vásquez1Kusisqa Saqra2Danitza DelCha3Renzo Aguirre4Universidad Nacional de San Agustin de ArequipaUniversidad Nacional de San Agustin de ArequipaUniversidad Nacional de San Agustin de ArequipaUniversidad Nacional de San Agustin de ArequipaUniversidad Nacional de San Agustin de Arequipa During the COVID-19 pandemic in Peru, a notable increase in self-medication with antibiotics has been observed, raising concerns about the increase in bacterial resistance. In this context, we evaluated the situation in wastewater treatment plants (WWTPs) using biochemical methods and sensitivity tests, such as the Kirby-Bauer assay. The results of our study show a high sensitivity to antibiotics in most of the strains analyzed, particularly towards β-lactams. However, this sensitivity appears to be influenced by seasonal patterns of medication consumption, supported by studies indicating that its contribution to the total flow is minimal. We analyzed 49 strains of Escherichia coli, 27% of which showed no resistance to any antibiotic, while the highest resistance was observed against tetracycline (63%). High levels of resistance to fluoroquinolones, such as ciprofloxacin and levofloxacin, were also recorded. In contrast, amikacin and piperacillin-tazobactam showed minimal resistance, with only one strain resistant to each. Multiresistance, defined as resistance to at least two antibiotics, was identified in 35% of the strains, with two of them showing resistance to 8 and 10 antibiotics, respectively. https://revistas.udea.edu.co/index.php/ingenieria/article/view/355727E. coliAMRAntimicrobial ResistanceResistance ProfileWWTP |
| spellingShingle | Isaac Yanqui-Morales Ricardo León-Vásquez Kusisqa Saqra Danitza DelCha Renzo Aguirre Situational status of antibiotic resistance of E. coli in the Escalerilla WWTP, Arequipa, Peru Revista Facultad de Ingeniería Universidad de Antioquia E. coli AMR Antimicrobial Resistance Resistance Profile WWTP |
| title | Situational status of antibiotic resistance of E. coli in the Escalerilla WWTP, Arequipa, Peru |
| title_full | Situational status of antibiotic resistance of E. coli in the Escalerilla WWTP, Arequipa, Peru |
| title_fullStr | Situational status of antibiotic resistance of E. coli in the Escalerilla WWTP, Arequipa, Peru |
| title_full_unstemmed | Situational status of antibiotic resistance of E. coli in the Escalerilla WWTP, Arequipa, Peru |
| title_short | Situational status of antibiotic resistance of E. coli in the Escalerilla WWTP, Arequipa, Peru |
| title_sort | situational status of antibiotic resistance of e coli in the escalerilla wwtp arequipa peru |
| topic | E. coli AMR Antimicrobial Resistance Resistance Profile WWTP |
| url | https://revistas.udea.edu.co/index.php/ingenieria/article/view/355727 |
| work_keys_str_mv | AT isaacyanquimorales situationalstatusofantibioticresistanceofecoliintheescalerillawwtparequipaperu AT ricardoleonvasquez situationalstatusofantibioticresistanceofecoliintheescalerillawwtparequipaperu AT kusisqasaqra situationalstatusofantibioticresistanceofecoliintheescalerillawwtparequipaperu AT danitzadelcha situationalstatusofantibioticresistanceofecoliintheescalerillawwtparequipaperu AT renzoaguirre situationalstatusofantibioticresistanceofecoliintheescalerillawwtparequipaperu |