Herbal Medicines as Complementary Therapy for Managing Complications in COVID-19 Patients with Diabetes Mellitus
Syah Akbarul Adha,1 Nadiya Nurul Afifah,1,2 Irma Rahayu Latarissa,3,4 Ghina Nadhifah Iftinan,4 Arif Satria Wira Kusuma,1,2 Raden Maya Febriyanti,1 Melisa Intan Barliana,1,2 Keri Lestari2– 4 1Department of Biological Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia; 2Center...
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| Language: | English |
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Dove Medical Press
2025-01-01
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| Series: | Diabetes, Metabolic Syndrome and Obesity |
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| Online Access: | https://www.dovepress.com/herbal-medicines-as-complementary-therapy-for-managing-complications-i-peer-reviewed-fulltext-article-DMSO |
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| author | Adha SA Afifah NN Latarissa IR Iftinan GN Kusuma ASW Febriyanti RM Barliana MI Lestari K |
| author_facet | Adha SA Afifah NN Latarissa IR Iftinan GN Kusuma ASW Febriyanti RM Barliana MI Lestari K |
| author_sort | Adha SA |
| collection | DOAJ |
| description | Syah Akbarul Adha,1 Nadiya Nurul Afifah,1,2 Irma Rahayu Latarissa,3,4 Ghina Nadhifah Iftinan,4 Arif Satria Wira Kusuma,1,2 Raden Maya Febriyanti,1 Melisa Intan Barliana,1,2 Keri Lestari2– 4 1Department of Biological Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia; 2Center of Excellence for Pharmaceutical Care Innovation, Universitas Padjadjaran, Sumedang, Indonesia; 3Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia; 4Medication Therapy Adherence Clinic (MTAC), Universitas Padjadjaran, Sumedang, IndonesiaCorrespondence: Keri Lestari, Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Jl. Raya Bandung Sumedang KM. 21, Jatinangor, 45363, Indonesia, Email lestarikd@unpad.ac.idAbstract: Diabetes mellitus (DM) is recognized and classified as a group of conditions marked by persistent high blood glucose levels. It is also an inflammatory condition that may influence concurrent disease states, including Coronavirus Disease 2019 (COVID-19). Currently, no effective drug has been found to treat COVID-19, especially in DM patients. Many herbal medicines, such as the well-known Andrographis paniculata, have been explored as drugs and complementary therapies due to their antidiabetic, antibacterial, antiviral, anti-inflammatory, and immunomodulatory effects. This study aimed to examine the potential of herbal medicines as complementary therapy in DM patients with COVID-19 complications, drawing from in-vitro and in-vivo investigations. This study analyzed articles published within the last 15 years using keywords including “herbal medicines”, “COVID-19”, “Diabetes Mellitus”, “antidiabetics”, “antiviral”, and “anti-inflammatory”. The results showed that several herbal medicines could serve as complementary therapy for DM patients with COVID-19 complications. These include Andrographis paniculata, Ageratum conyzoides, Artocarpus altilis, Centella asiatica, Momordica charantia, Persea gratissima, Phyllanthus urinaria, Physalis angulata, Tinospora cordifolia, and Zingiber zerumbet. Herbal medicines may serve as a complementary therapy for DM patients with COVID-19, but these claims need experimental validation in infection models and among affected patients.Keywords: COVID-19, diabetes mellitus, antidiabetic, immunomodulator, anti-inflammatory, herbal medicines |
| format | Article |
| id | doaj-art-9e5772f5fb774ba1b24ad6c877d9d64c |
| institution | Kabale University |
| issn | 1178-7007 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Diabetes, Metabolic Syndrome and Obesity |
| spelling | doaj-art-9e5772f5fb774ba1b24ad6c877d9d64c2025-01-16T16:17:13ZengDove Medical PressDiabetes, Metabolic Syndrome and Obesity1178-70072025-01-01Volume 1813514699284Herbal Medicines as Complementary Therapy for Managing Complications in COVID-19 Patients with Diabetes MellitusAdha SAAfifah NNLatarissa IRIftinan GNKusuma ASWFebriyanti RMBarliana MILestari KSyah Akbarul Adha,1 Nadiya Nurul Afifah,1,2 Irma Rahayu Latarissa,3,4 Ghina Nadhifah Iftinan,4 Arif Satria Wira Kusuma,1,2 Raden Maya Febriyanti,1 Melisa Intan Barliana,1,2 Keri Lestari2– 4 1Department of Biological Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia; 2Center of Excellence for Pharmaceutical Care Innovation, Universitas Padjadjaran, Sumedang, Indonesia; 3Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia; 4Medication Therapy Adherence Clinic (MTAC), Universitas Padjadjaran, Sumedang, IndonesiaCorrespondence: Keri Lestari, Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Jl. Raya Bandung Sumedang KM. 21, Jatinangor, 45363, Indonesia, Email lestarikd@unpad.ac.idAbstract: Diabetes mellitus (DM) is recognized and classified as a group of conditions marked by persistent high blood glucose levels. It is also an inflammatory condition that may influence concurrent disease states, including Coronavirus Disease 2019 (COVID-19). Currently, no effective drug has been found to treat COVID-19, especially in DM patients. Many herbal medicines, such as the well-known Andrographis paniculata, have been explored as drugs and complementary therapies due to their antidiabetic, antibacterial, antiviral, anti-inflammatory, and immunomodulatory effects. This study aimed to examine the potential of herbal medicines as complementary therapy in DM patients with COVID-19 complications, drawing from in-vitro and in-vivo investigations. This study analyzed articles published within the last 15 years using keywords including “herbal medicines”, “COVID-19”, “Diabetes Mellitus”, “antidiabetics”, “antiviral”, and “anti-inflammatory”. The results showed that several herbal medicines could serve as complementary therapy for DM patients with COVID-19 complications. These include Andrographis paniculata, Ageratum conyzoides, Artocarpus altilis, Centella asiatica, Momordica charantia, Persea gratissima, Phyllanthus urinaria, Physalis angulata, Tinospora cordifolia, and Zingiber zerumbet. Herbal medicines may serve as a complementary therapy for DM patients with COVID-19, but these claims need experimental validation in infection models and among affected patients.Keywords: COVID-19, diabetes mellitus, antidiabetic, immunomodulator, anti-inflammatory, herbal medicineshttps://www.dovepress.com/herbal-medicines-as-complementary-therapy-for-managing-complications-i-peer-reviewed-fulltext-article-DMSOcovid-19diabetes mellitusantidiabeticimmunomodulatoranti-inflammatoryherbal medicines |
| spellingShingle | Adha SA Afifah NN Latarissa IR Iftinan GN Kusuma ASW Febriyanti RM Barliana MI Lestari K Herbal Medicines as Complementary Therapy for Managing Complications in COVID-19 Patients with Diabetes Mellitus Diabetes, Metabolic Syndrome and Obesity covid-19 diabetes mellitus antidiabetic immunomodulator anti-inflammatory herbal medicines |
| title | Herbal Medicines as Complementary Therapy for Managing Complications in COVID-19 Patients with Diabetes Mellitus |
| title_full | Herbal Medicines as Complementary Therapy for Managing Complications in COVID-19 Patients with Diabetes Mellitus |
| title_fullStr | Herbal Medicines as Complementary Therapy for Managing Complications in COVID-19 Patients with Diabetes Mellitus |
| title_full_unstemmed | Herbal Medicines as Complementary Therapy for Managing Complications in COVID-19 Patients with Diabetes Mellitus |
| title_short | Herbal Medicines as Complementary Therapy for Managing Complications in COVID-19 Patients with Diabetes Mellitus |
| title_sort | herbal medicines as complementary therapy for managing complications in covid 19 patients with diabetes mellitus |
| topic | covid-19 diabetes mellitus antidiabetic immunomodulator anti-inflammatory herbal medicines |
| url | https://www.dovepress.com/herbal-medicines-as-complementary-therapy-for-managing-complications-i-peer-reviewed-fulltext-article-DMSO |
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