Validation of polymorphic Gompertzian model of cancer through in vitro and in vivo data.
Mathematical modeling plays an important role in our understanding and targeting therapy resistance mechanisms in cancer. The polymorphic Gompertzian model, analyzed theoretically and numerically by Viossat and Noble to demonstrate the benefits of adaptive therapy in metastatic cancer, describes a h...
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Main Authors: | Arina Soboleva, Artem Kaznatcheev, Rachel Cavill, Katharina Schneider, Kateřina Staňková |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2025-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0310844 |
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