Anxiety and depression severity in neuropsychiatric SLE are associated with perfusion and functional connectivity changes of the frontolimbic neural circuit: a resting-state f(unctional) MRI study

Anxiety and depression severity in neuropsychiatric SLE are associated with perfusion and functional connectivity changes of the frontolimbic neural circuit: a resting-state f(unctional) MRI study

Objective To examine the hypothesis that perfusion and functional connectivity disturbances in brain areas implicated in emotional processing are linked to emotion-related symptoms in neuropsychiatric SLE (NPSLE).Methods Resting-state fMRI (rs-fMRI) was performed and anxiety and/or depression sympto...

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Bibliographic Details
Main Authors: Efrosini Papadaki, Antonis Fanouriakis, Eleftherios Kavroulakis, Prodromos Sidiropoulos, George Bertsias, Dimitrios Boumpas, Despina Antypa, Nicholas J Simos
Format: Article
Language:English
Published: BMJ Publishing Group 2021-05-01
Series:Lupus Science and Medicine
Online Access:https://lupus.bmj.com/content/8/1/e000473.full
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