Sequencing of Argonaute-bound microRNA/mRNA hybrids reveals regulation of the unfolded protein response by microRNA-320a.

Sequencing of Argonaute-bound microRNA/mRNA hybrids reveals regulation of the unfolded protein response by microRNA-320a.

MicroRNAs (miRNA) are short non-coding RNAs widely implicated in gene regulation. Most metazoan miRNAs utilize the RNase III enzymes Drosha and Dicer for biogenesis. One notable exception is the RNA polymerase II transcription start sites (TSS) miRNAs whose biogenesis does not require Drosha. The fu...

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Bibliographic Details
Main Authors: Christopher J Fields, Lu Li, Nicholas M Hiers, Tianqi Li, Peike Sheng, Taha Huda, Jixiu Shan, Lauren Gay, Tongjun Gu, Jiang Bian, Michael S Kilberg, Rolf Renne, Mingyi Xie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-12-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1009934&type=printable
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https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1009934&type=printable

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