Synthesis, structure, and antimicrobial activity of aminated 5-chloro-6-nitrobenzofurazan with substituted anilines
A simple and efficient procedure for synthesis of nucleophilc aromatic substitution products in benzofurazan cycle on the basis of reactions of substituted anilines with 5-chloro-6-nitrobenzofurazan has been elaborated. The obtained products have a broad spectrum of antibacterial and antimycotic ac...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Kazan Federal University
2017-12-01
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| Series: | Учёные записки Казанского университета: Серия Естественные науки |
| Subjects: | |
| Online Access: | https://kpfu.ru/synthesis-structure-and-antimicrobial-activity-of.html |
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| Summary: | A simple and efficient procedure for synthesis of nucleophilc aromatic substitution products in benzofurazan cycle on the basis of reactions of substituted anilines with 5-chloro-6-nitrobenzofurazan has been elaborated. The obtained products have a broad spectrum of antibacterial and antimycotic activity. The structure of compounds has been confirmed by IR-, NMR-spectroscopy and also by single-crystal X-ray analysis. Thermal stability of the products has been studied by the combined method of thermogravimetry and differential scanning calorimetry (TG-DSC). |
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| ISSN: | 2542-064X 2500-218X |