FOCUS-GUIDED ENDOMYOCARDIAL BYOPSY IN DIAGNOSTICS OF ARRHYTHMOGENIC DYSPLASIA OF THE RIGHT VENTRICLE IN PATIENTS SCHEDULED FOR CATHETER ABLATION OF VENTRICULAR ARRHYTHMIAS
Endomyocardial biopsy (EMB) is one of diagnostical tools for arrhythmogenicdysplasia of the right ventricle (ADRB). However sensitivity and specificity of EMBrelay on the methodics of its performing.Aim. To compare “focus-guided” and “voluntary” EMB in diagnostics of ADRB inpatients, scheduled for c...
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«FIRMA «SILICEA» LLC
2016-07-01
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| Series: | Российский кардиологический журнал |
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| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/867 |
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| author | K. A. Simonova E. N. Mikhaylov E R. V. Tatarsky L. B. Mitrofanova D. S. Lebedev |
| author_facet | K. A. Simonova E. N. Mikhaylov E R. V. Tatarsky L. B. Mitrofanova D. S. Lebedev |
| author_sort | K. A. Simonova |
| collection | DOAJ |
| description | Endomyocardial biopsy (EMB) is one of diagnostical tools for arrhythmogenicdysplasia of the right ventricle (ADRB). However sensitivity and specificity of EMBrelay on the methodics of its performing.Aim. To compare “focus-guided” and “voluntary” EMB in diagnostics of ADRB inpatients, scheduled for catheter ablation of ventricular rhythm disorders. Material and methods. To retrospective study 122 patients included, among those scheduled for catheter ablation of ventricular tachicardia and\or sympthomatic ventricular extrasystoly, underwent EMB (64 males, mean age 39±14 y.). Patients were selected to 2 groups: 1) 44 patients (36%) with “focus-guided” biopsy (minimum 1 fragment of endomyocardium from the area(s) of ectopy); 2) 78 patients (64%) with “voluntary” EMB (specimens taken from any area except the focus).Results. Sixteen (13,1%) patients took the definite dignosis of ADRB according to 2010 Criteria. Short-term effect of ablation reached 69,7% of patients, much less efficacy had ADRB group (43,8%). Sensitivity and specificity of EMB in the big criteria of ADRB revealing, by histology, was higher in the group with “focus-guided” EMB, comparing to the “voluntary” group (100% and 91,7% vs. 80% and 81,4%, respectively).Conclusion. To improve sensitivity and specificity of EMB in ADRB diagnostics it is aimful to take myocardium specimens from the area of researched ventricular ectopy. |
| format | Article |
| id | doaj-art-9dfd14c5e4b24e5bbec4f27a2e4cdb51 |
| institution | Kabale University |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| publishDate | 2016-07-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj-art-9dfd14c5e4b24e5bbec4f27a2e4cdb512025-08-20T03:43:37Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202016-07-0107889210.15829/1560-4071-2016-7-88-92750FOCUS-GUIDED ENDOMYOCARDIAL BYOPSY IN DIAGNOSTICS OF ARRHYTHMOGENIC DYSPLASIA OF THE RIGHT VENTRICLE IN PATIENTS SCHEDULED FOR CATHETER ABLATION OF VENTRICULAR ARRHYTHMIASK. A. Simonova0E. N. Mikhaylov E1R. V. Tatarsky2L. B. Mitrofanova3D. S. Lebedev4Federal Almazov North-West Medical Research Centre of the Ministry of Health, Saint-Petersburg, Russia.Federal Almazov North-West Medical Research Centre of the Ministry of Health, Saint-Petersburg, Russia.Federal Almazov North-West Medical Research Centre of the Ministry of Health, Saint-Petersburg, Russia.Federal Almazov North-West Medical Research Centre of the Ministry of Health, Saint-Petersburg, Russia.Federal Almazov North-West Medical Research Centre of the Ministry of Health, Saint-Petersburg, Russia.Endomyocardial biopsy (EMB) is one of diagnostical tools for arrhythmogenicdysplasia of the right ventricle (ADRB). However sensitivity and specificity of EMBrelay on the methodics of its performing.Aim. To compare “focus-guided” and “voluntary” EMB in diagnostics of ADRB inpatients, scheduled for catheter ablation of ventricular rhythm disorders. Material and methods. To retrospective study 122 patients included, among those scheduled for catheter ablation of ventricular tachicardia and\or sympthomatic ventricular extrasystoly, underwent EMB (64 males, mean age 39±14 y.). Patients were selected to 2 groups: 1) 44 patients (36%) with “focus-guided” biopsy (minimum 1 fragment of endomyocardium from the area(s) of ectopy); 2) 78 patients (64%) with “voluntary” EMB (specimens taken from any area except the focus).Results. Sixteen (13,1%) patients took the definite dignosis of ADRB according to 2010 Criteria. Short-term effect of ablation reached 69,7% of patients, much less efficacy had ADRB group (43,8%). Sensitivity and specificity of EMB in the big criteria of ADRB revealing, by histology, was higher in the group with “focus-guided” EMB, comparing to the “voluntary” group (100% and 91,7% vs. 80% and 81,4%, respectively).Conclusion. To improve sensitivity and specificity of EMB in ADRB diagnostics it is aimful to take myocardium specimens from the area of researched ventricular ectopy.https://russjcardiol.elpub.ru/jour/article/view/867arrhythmogenic dysplasia of right ventricleendomyocardial byopsyventricular ectopyradiofrequency ablation |
| spellingShingle | K. A. Simonova E. N. Mikhaylov E R. V. Tatarsky L. B. Mitrofanova D. S. Lebedev FOCUS-GUIDED ENDOMYOCARDIAL BYOPSY IN DIAGNOSTICS OF ARRHYTHMOGENIC DYSPLASIA OF THE RIGHT VENTRICLE IN PATIENTS SCHEDULED FOR CATHETER ABLATION OF VENTRICULAR ARRHYTHMIAS Российский кардиологический журнал arrhythmogenic dysplasia of right ventricle endomyocardial byopsy ventricular ectopy radiofrequency ablation |
| title | FOCUS-GUIDED ENDOMYOCARDIAL BYOPSY IN DIAGNOSTICS OF ARRHYTHMOGENIC DYSPLASIA OF THE RIGHT VENTRICLE IN PATIENTS SCHEDULED FOR CATHETER ABLATION OF VENTRICULAR ARRHYTHMIAS |
| title_full | FOCUS-GUIDED ENDOMYOCARDIAL BYOPSY IN DIAGNOSTICS OF ARRHYTHMOGENIC DYSPLASIA OF THE RIGHT VENTRICLE IN PATIENTS SCHEDULED FOR CATHETER ABLATION OF VENTRICULAR ARRHYTHMIAS |
| title_fullStr | FOCUS-GUIDED ENDOMYOCARDIAL BYOPSY IN DIAGNOSTICS OF ARRHYTHMOGENIC DYSPLASIA OF THE RIGHT VENTRICLE IN PATIENTS SCHEDULED FOR CATHETER ABLATION OF VENTRICULAR ARRHYTHMIAS |
| title_full_unstemmed | FOCUS-GUIDED ENDOMYOCARDIAL BYOPSY IN DIAGNOSTICS OF ARRHYTHMOGENIC DYSPLASIA OF THE RIGHT VENTRICLE IN PATIENTS SCHEDULED FOR CATHETER ABLATION OF VENTRICULAR ARRHYTHMIAS |
| title_short | FOCUS-GUIDED ENDOMYOCARDIAL BYOPSY IN DIAGNOSTICS OF ARRHYTHMOGENIC DYSPLASIA OF THE RIGHT VENTRICLE IN PATIENTS SCHEDULED FOR CATHETER ABLATION OF VENTRICULAR ARRHYTHMIAS |
| title_sort | focus guided endomyocardial byopsy in diagnostics of arrhythmogenic dysplasia of the right ventricle in patients scheduled for catheter ablation of ventricular arrhythmias |
| topic | arrhythmogenic dysplasia of right ventricle endomyocardial byopsy ventricular ectopy radiofrequency ablation |
| url | https://russjcardiol.elpub.ru/jour/article/view/867 |
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