Outcomes of nephrostomy and double J stent in malignant ureteral obstruction in the Palestinian practice
Abstract Background Malignant ureteral obstruction (MUO) is a serious health condition in which a malignant tumor compresses the ureter. The optimal decompressive intervention in MUO remains unclear. This study was conducted to assess and compare renal function, the occurrence of ureterohydronephros...
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BMC
2024-11-01
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| Series: | BMC Urology |
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| Online Access: | https://doi.org/10.1186/s12894-024-01640-3 |
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| author | Elisa Ghannam Helen Musleh Tamara Ahmad Mahmoud Mustafa Razan Odeh Ramzi Shawahna |
| author_facet | Elisa Ghannam Helen Musleh Tamara Ahmad Mahmoud Mustafa Razan Odeh Ramzi Shawahna |
| author_sort | Elisa Ghannam |
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| description | Abstract Background Malignant ureteral obstruction (MUO) is a serious health condition in which a malignant tumor compresses the ureter. The optimal decompressive intervention in MUO remains unclear. This study was conducted to assess and compare renal function, the occurrence of ureterohydronephrosis (UHN), intraoperative, and postoperative complications among patients with MUO who underwent double J stenting (DJS) and percutaneous nephrostomy (PCN) in the Palestinian practice. Methods This study was conducted in retrospective design in one of the main tertiary care hospitals in the West Bank of Palestine. The data were collected from the electronic health information system of the hospital for the patients with MUO who received either DJS or PCN as a decompressive intervention from January 2018 to January 2024. Results In this retrospective analysis, 62 patients who had stage 2 to stage 4 cancer and suffered MUO were included. The mean age of the patients was 60.8 ± 13.6 years. Of the patients, 40 (64.5%) were male and 22 (35.5%) were female. Of the patients, 26 (41.9%) had urinary bladder cancer. Of the patients, 23 (37.1%) had flank pain and 16 (25.8%) had lower urinary tract symptoms. Of the patients, 34 (54.8%) experienced bilateral UHN and 28 (45.2%) experienced unilateral UHN. In this study, 43 patients (69.4%) received PCN, and 19 (30.6%) received DJS as a decompressive intervention. Of the patients, 36 (58.1%) suffered postoperative complications. Stent migration/slip, UTIs, and urosepsis were the most commonly reported postoperative complications. There were no statistically significant differences in the occurrence of intraoperative complications, postoperative complications, time elapsed from receiving the decompression intervention to the diagnosis of complications, ICU admission, prognosis of UHN, serum creatinine, and serum BUN between both decompressive interventions. Conclusion Despite improvements in renal functions, creatinine and BUN levels remained abnormal even after receiving a decompressive intervention. Postoperative complications were frequently reported among patients who received DJS or PCN as decompressive interventions. Larger prospective studies are still needed to determine the optimal interventions to improve outcomes, quality of life, and survival rates of patients with DJS or PCN. |
| format | Article |
| id | doaj-art-9dcef07896fb41248239b3ea69036d3f |
| institution | Kabale University |
| issn | 1471-2490 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | BMC |
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| series | BMC Urology |
| spelling | doaj-art-9dcef07896fb41248239b3ea69036d3f2024-11-10T12:44:17ZengBMCBMC Urology1471-24902024-11-012411910.1186/s12894-024-01640-3Outcomes of nephrostomy and double J stent in malignant ureteral obstruction in the Palestinian practiceElisa Ghannam0Helen Musleh1Tamara Ahmad2Mahmoud Mustafa3Razan Odeh4Ramzi Shawahna5Department of Medicine, Faculty of Medicine and Health Sciences, An-Najah National UniversityDepartment of Medicine, Faculty of Medicine and Health Sciences, An-Najah National UniversityDepartment of Medicine, Faculty of Medicine and Health Sciences, An-Najah National UniversityDepartment of Medicine, Faculty of Medicine and Health Sciences, An-Najah National UniversityDepartment of Medicine, Faculty of Medicine and Health Sciences, An-Najah National UniversityDepartment of Physiology, Pharmacology, and Toxicology, Faculty of Medicine and Health Sciences, An-Najah National UniversityAbstract Background Malignant ureteral obstruction (MUO) is a serious health condition in which a malignant tumor compresses the ureter. The optimal decompressive intervention in MUO remains unclear. This study was conducted to assess and compare renal function, the occurrence of ureterohydronephrosis (UHN), intraoperative, and postoperative complications among patients with MUO who underwent double J stenting (DJS) and percutaneous nephrostomy (PCN) in the Palestinian practice. Methods This study was conducted in retrospective design in one of the main tertiary care hospitals in the West Bank of Palestine. The data were collected from the electronic health information system of the hospital for the patients with MUO who received either DJS or PCN as a decompressive intervention from January 2018 to January 2024. Results In this retrospective analysis, 62 patients who had stage 2 to stage 4 cancer and suffered MUO were included. The mean age of the patients was 60.8 ± 13.6 years. Of the patients, 40 (64.5%) were male and 22 (35.5%) were female. Of the patients, 26 (41.9%) had urinary bladder cancer. Of the patients, 23 (37.1%) had flank pain and 16 (25.8%) had lower urinary tract symptoms. Of the patients, 34 (54.8%) experienced bilateral UHN and 28 (45.2%) experienced unilateral UHN. In this study, 43 patients (69.4%) received PCN, and 19 (30.6%) received DJS as a decompressive intervention. Of the patients, 36 (58.1%) suffered postoperative complications. Stent migration/slip, UTIs, and urosepsis were the most commonly reported postoperative complications. There were no statistically significant differences in the occurrence of intraoperative complications, postoperative complications, time elapsed from receiving the decompression intervention to the diagnosis of complications, ICU admission, prognosis of UHN, serum creatinine, and serum BUN between both decompressive interventions. Conclusion Despite improvements in renal functions, creatinine and BUN levels remained abnormal even after receiving a decompressive intervention. Postoperative complications were frequently reported among patients who received DJS or PCN as decompressive interventions. Larger prospective studies are still needed to determine the optimal interventions to improve outcomes, quality of life, and survival rates of patients with DJS or PCN.https://doi.org/10.1186/s12894-024-01640-3JJ stentingMalignant ureteral obstructionOncologyPercutaneous nephrostomyUreterohydronephrosisUrology |
| spellingShingle | Elisa Ghannam Helen Musleh Tamara Ahmad Mahmoud Mustafa Razan Odeh Ramzi Shawahna Outcomes of nephrostomy and double J stent in malignant ureteral obstruction in the Palestinian practice BMC Urology JJ stenting Malignant ureteral obstruction Oncology Percutaneous nephrostomy Ureterohydronephrosis Urology |
| title | Outcomes of nephrostomy and double J stent in malignant ureteral obstruction in the Palestinian practice |
| title_full | Outcomes of nephrostomy and double J stent in malignant ureteral obstruction in the Palestinian practice |
| title_fullStr | Outcomes of nephrostomy and double J stent in malignant ureteral obstruction in the Palestinian practice |
| title_full_unstemmed | Outcomes of nephrostomy and double J stent in malignant ureteral obstruction in the Palestinian practice |
| title_short | Outcomes of nephrostomy and double J stent in malignant ureteral obstruction in the Palestinian practice |
| title_sort | outcomes of nephrostomy and double j stent in malignant ureteral obstruction in the palestinian practice |
| topic | JJ stenting Malignant ureteral obstruction Oncology Percutaneous nephrostomy Ureterohydronephrosis Urology |
| url | https://doi.org/10.1186/s12894-024-01640-3 |
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