ProbC: joint modeling of epigenome and transcriptome effects in 3D genome

Abstract Background Hi-C and its high nucleosome resolution variant Micro-C provide a window into the spatial packing of a genome in 3D within the cell. Even though both techniques do not directly depend on the binding of specific antibodies, previous work has revealed enriched interactions and doma...

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Bibliographic Details
Main Author: Emre Sefer
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-022-08498-5
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