Human iPSC-derived microglial cells protect neurons from neurodegeneration in long-term cultured adhesion brain organoids
Abstract Brain organoid models have greatly facilitated our understanding of human brain development and disease. However, key brain cell types, such as microglia, are lacking in most brain organoid models. Because microglia have been shown to play important roles in brain development and pathologie...
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Main Authors: | Xianwei Chen, Guoqiang Sun, Lizhao Feng, E Tian, Yanhong Shi |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-024-07401-0 |
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