Machine learning framework for investigating nano- and micro-scale particle diffusion in colonic mucus

Machine learning framework for investigating nano- and micro-scale particle diffusion in colonic mucus

Abstract Biosimilar artificial mucus models that mimic native mucus facilitate efficient, lab-based drug diffusion studies, addressing the costly and challenging preclinical phase of drug development, especially for nano- and micro-scale particle-based colonic drug delivery. This study presents a ma...

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Bibliographic Details
Main Authors: Marco Tjakra, Kristína Lidayová, Christophe Avenel, Christel A.S. Bergström, Shakhawath Hossain
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Journal of Nanobiotechnology
Subjects:
Mucus
Machine learning
Diffusion
Nanoparticles
Rheology
Online Access:https://doi.org/10.1186/s12951-025-03659-6
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https://doi.org/10.1186/s12951-025-03659-6

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