Clinicopathological analysis of potentially malignant and malignant verrucopapillary lesions of the oral cavity – A literature review

Aims: This review article aims to provide an in-depth analysis of potentially malignant and malignant verrucopapillary lesions, including their etiology, clinical and histological features, differential diagnosis, and immunohistochemical analysis. Background: The word verrucopapillary lesions (VPL)...

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Main Authors: Baishakhi Modak, Spoorti Kulkarni
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:Oral Oncology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772906024004333
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author Baishakhi Modak
Spoorti Kulkarni
author_facet Baishakhi Modak
Spoorti Kulkarni
author_sort Baishakhi Modak
collection DOAJ
description Aims: This review article aims to provide an in-depth analysis of potentially malignant and malignant verrucopapillary lesions, including their etiology, clinical and histological features, differential diagnosis, and immunohistochemical analysis. Background: The word verrucopapillary lesions (VPL) refers to a variety of lesions in the oral region, ranging from benign to completely malignant tumors. They cause surface changes that can be seen as ulcerative, vesiculobullous, or papillary/papular/polypoid lesions, altering the usual morphology and stability of the mucosa. Review results: The clinical, histopathological and immunohistochemical characteristics of oral verrucopapillary lesions may help in their accurate diagnosis. Clinical significance: Verrucous and papillary lesions of the oral cavity are diagnostically challenging because of similar clinical presentation. The current understanding of potentially malignant VPLs is perplexing due to numerous terminologies. Many of the controversies in these entities are due to the lack of consensus on the disease characteristics and management.
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series Oral Oncology Reports
spelling doaj-art-9cf7e593bc9343159c843e84d1528dba2025-01-09T06:16:50ZengElsevierOral Oncology Reports2772-90602024-09-0111100587Clinicopathological analysis of potentially malignant and malignant verrucopapillary lesions of the oral cavity – A literature reviewBaishakhi Modak0Spoorti Kulkarni1Department of Oral and Maxillofacial Pathology and Oral Microbiology, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, IndiaCorresponding author.; Department of Oral and Maxillofacial Pathology and Oral Microbiology, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, IndiaAims: This review article aims to provide an in-depth analysis of potentially malignant and malignant verrucopapillary lesions, including their etiology, clinical and histological features, differential diagnosis, and immunohistochemical analysis. Background: The word verrucopapillary lesions (VPL) refers to a variety of lesions in the oral region, ranging from benign to completely malignant tumors. They cause surface changes that can be seen as ulcerative, vesiculobullous, or papillary/papular/polypoid lesions, altering the usual morphology and stability of the mucosa. Review results: The clinical, histopathological and immunohistochemical characteristics of oral verrucopapillary lesions may help in their accurate diagnosis. Clinical significance: Verrucous and papillary lesions of the oral cavity are diagnostically challenging because of similar clinical presentation. The current understanding of potentially malignant VPLs is perplexing due to numerous terminologies. Many of the controversies in these entities are due to the lack of consensus on the disease characteristics and management.http://www.sciencedirect.com/science/article/pii/S2772906024004333Verrucopapillary lesionsMalignantPotentially malignant verrucous lesions
spellingShingle Baishakhi Modak
Spoorti Kulkarni
Clinicopathological analysis of potentially malignant and malignant verrucopapillary lesions of the oral cavity – A literature review
Oral Oncology Reports
Verrucopapillary lesions
Malignant
Potentially malignant verrucous lesions
title Clinicopathological analysis of potentially malignant and malignant verrucopapillary lesions of the oral cavity – A literature review
title_full Clinicopathological analysis of potentially malignant and malignant verrucopapillary lesions of the oral cavity – A literature review
title_fullStr Clinicopathological analysis of potentially malignant and malignant verrucopapillary lesions of the oral cavity – A literature review
title_full_unstemmed Clinicopathological analysis of potentially malignant and malignant verrucopapillary lesions of the oral cavity – A literature review
title_short Clinicopathological analysis of potentially malignant and malignant verrucopapillary lesions of the oral cavity – A literature review
title_sort clinicopathological analysis of potentially malignant and malignant verrucopapillary lesions of the oral cavity a literature review
topic Verrucopapillary lesions
Malignant
Potentially malignant verrucous lesions
url http://www.sciencedirect.com/science/article/pii/S2772906024004333
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AT spoortikulkarni clinicopathologicalanalysisofpotentiallymalignantandmalignantverrucopapillarylesionsoftheoralcavityaliteraturereview