Multi-omics analysis reveals the role of the autophagy-related gene AGT in chemotherapy resistance in colorectal cancer and the therapeutic potential of its inhibitors
Abstract Background Autophagy is a crucial mechanism for maintaining cellular homeostasis and responding to environmental stress, and it is closely linked to tumor drug resistance. Through multi-omics analysis, this study explores the expression patterns, functions, and potential role of the autopha...
Saved in:
| Main Authors: | Wenjiao Cai, Tao Xiang, Xiaoli Liu, Chong Fu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2024-11-01
|
| Series: | Discover Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s12672-024-01545-5 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Assessment of male football players’ physical fitness levels based on certain gene (AGT rs699 & IL-6 rs1800795) polymorphisms
by: Celal Bulgay, et al.
Published: (2025-04-01) -
Multidimensional bioinformatics analysis reveals the potential carcinogenic role of acrylamide in colorectal cancer
by: Xiaopeng Yu, et al.
Published: (2025-06-01) -
Autophagy inhibition improves sensitivity to the multi-kinase inhibitor regorafenib in preclinical mouse colon tumoroids
by: Giulia Agostini, et al.
Published: (2025-07-01) -
Gut microbiota influences colorectal cancer through immune cell interactions: a Mendelian randomization study
by: Linyi Zheng, et al.
Published: (2025-05-01) -
Gut microbiota interplay with autophagy-EMT dynamics in colorectal cancer
by: Tiziana Vescovo, et al.
Published: (2025-08-01)