Analysis of Cognitive Levels and Influencing Factors in Children with Obstructive Sleep Apnea

Background: Obstructive sleep apnea (OSA) in children is prevalent worldwide and affects their physiological, psychological, and cognitive functions. However, the research on OSA’s impact on children’s cognitive function remains inconclusive. This study aims to analyze the cognitive levels and influ...

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Main Authors: Jing Bi, Bo Yu, Guotong Zheng, Yangyan Yan, Yang Zhang, Xiaoyan Lin, Yiyuan Han, Chao Song
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Children
Subjects:
Online Access:https://www.mdpi.com/2227-9067/11/12/1428
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author Jing Bi
Bo Yu
Guotong Zheng
Yangyan Yan
Yang Zhang
Xiaoyan Lin
Yiyuan Han
Chao Song
author_facet Jing Bi
Bo Yu
Guotong Zheng
Yangyan Yan
Yang Zhang
Xiaoyan Lin
Yiyuan Han
Chao Song
author_sort Jing Bi
collection DOAJ
description Background: Obstructive sleep apnea (OSA) in children is prevalent worldwide and affects their physiological, psychological, and cognitive functions. However, the research on OSA’s impact on children’s cognitive function remains inconclusive. This study aims to analyze the cognitive levels and influencing factors in children with OSA in a single-center study in China. Methods: We selected 110 children with OSA who visited the Department of Otorhinolaryngology, Head and Neck Surgery at the Children’s Hospital of Zhejiang University School of Medicine from March 2023 to April 2024. Cognitive function was assessed using the Wechsler Intelligence Scale for Children-Fourth Edition (WISC-IV), and data on the OAHI, BMI, lowest blood oxygen saturation, and tonsillar hypertrophy were collected. A correlation analysis was performed using SPSS Statistics 26.0. Results: The mean WISC-IV score of the children with OSA was 102.32, within the normal range. Gender and tonsillar grade had no significant effect on the cognitive levels. The BMI scores were significantly negatively correlated with verbal comprehension. The OAHI was weakly negatively correlated with perceptual reasoning but not with other cognitive dimensions. Conclusions: OSA may negatively affect specific cognitive domains in children, particularly perceptual reasoning and working memory. The BMI is a crucial factor influencing cognitive function in children with OSA. Future research should increase the sample size, include more variables, and conduct long-term follow-ups to comprehensively evaluate the influencing factors of OSA on children’s cognitive function.
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spelling doaj-art-9cb15e2593d247ee9c506c971abe4cb72024-12-27T14:17:41ZengMDPI AGChildren2227-90672024-11-011112142810.3390/children11121428Analysis of Cognitive Levels and Influencing Factors in Children with Obstructive Sleep ApneaJing Bi0Bo Yu1Guotong Zheng2Yangyan Yan3Yang Zhang4Xiaoyan Lin5Yiyuan Han6Chao Song7Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310051, ChinaChildren’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310051, ChinaChildren’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310051, ChinaChildren’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310051, ChinaChildren’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310051, ChinaChildren’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310051, ChinaChildren’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310051, ChinaChildren’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310051, ChinaBackground: Obstructive sleep apnea (OSA) in children is prevalent worldwide and affects their physiological, psychological, and cognitive functions. However, the research on OSA’s impact on children’s cognitive function remains inconclusive. This study aims to analyze the cognitive levels and influencing factors in children with OSA in a single-center study in China. Methods: We selected 110 children with OSA who visited the Department of Otorhinolaryngology, Head and Neck Surgery at the Children’s Hospital of Zhejiang University School of Medicine from March 2023 to April 2024. Cognitive function was assessed using the Wechsler Intelligence Scale for Children-Fourth Edition (WISC-IV), and data on the OAHI, BMI, lowest blood oxygen saturation, and tonsillar hypertrophy were collected. A correlation analysis was performed using SPSS Statistics 26.0. Results: The mean WISC-IV score of the children with OSA was 102.32, within the normal range. Gender and tonsillar grade had no significant effect on the cognitive levels. The BMI scores were significantly negatively correlated with verbal comprehension. The OAHI was weakly negatively correlated with perceptual reasoning but not with other cognitive dimensions. Conclusions: OSA may negatively affect specific cognitive domains in children, particularly perceptual reasoning and working memory. The BMI is a crucial factor influencing cognitive function in children with OSA. Future research should increase the sample size, include more variables, and conduct long-term follow-ups to comprehensively evaluate the influencing factors of OSA on children’s cognitive function.https://www.mdpi.com/2227-9067/11/12/1428childrenOSAinfluencing factorscognitive functioning
spellingShingle Jing Bi
Bo Yu
Guotong Zheng
Yangyan Yan
Yang Zhang
Xiaoyan Lin
Yiyuan Han
Chao Song
Analysis of Cognitive Levels and Influencing Factors in Children with Obstructive Sleep Apnea
Children
children
OSA
influencing factors
cognitive functioning
title Analysis of Cognitive Levels and Influencing Factors in Children with Obstructive Sleep Apnea
title_full Analysis of Cognitive Levels and Influencing Factors in Children with Obstructive Sleep Apnea
title_fullStr Analysis of Cognitive Levels and Influencing Factors in Children with Obstructive Sleep Apnea
title_full_unstemmed Analysis of Cognitive Levels and Influencing Factors in Children with Obstructive Sleep Apnea
title_short Analysis of Cognitive Levels and Influencing Factors in Children with Obstructive Sleep Apnea
title_sort analysis of cognitive levels and influencing factors in children with obstructive sleep apnea
topic children
OSA
influencing factors
cognitive functioning
url https://www.mdpi.com/2227-9067/11/12/1428
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