CT radiomics identifying non‐responders to neoadjuvant chemoradiotherapy among patients with locally advanced rectal cancer

CT radiomics identifying non‐responders to neoadjuvant chemoradiotherapy among patients with locally advanced rectal cancer

Abstract Background and Purpose Early detection of non‐response to neoadjuvant chemoradiotherapy (nCRT) for locally advanced colorectal cancer (LARC) remains challenging. We aimed to assess whether pretreatment radiotherapy planning computed tomography (CT) radiomics could distinguish the patients w...

Full description

Saved in:

Bibliographic Details
Main Authors:	Zinan Zhang, Xiaoping Yi, Qian Pei, Yan Fu, Bin Li, Haipeng Liu, Zaide Han, Changyong Chen, Peipei Pang, Huashan Lin, Guanghui Gong, Hongling Yin, Hongyan Zai, Bihong T. Chen
Format:	Article
Language:	English
Published:	Wiley 2023-02-01
Series:	Cancer Medicine
Subjects:	CT radiomics locally advanced colorectal cancer neoadjuvant chemoradiotherapy prediction radiotherapy planning treatment response
Online Access:	https://doi.org/10.1002/cam4.5086
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Neoadjuvant chemoradiotherapy in combined treatment of patients with rectal cancer
by: N. A. Maistrenko, et al.
Published: (2017-08-01)

Role of mast cell in locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy
by: Masaaki Nishi, et al.
Published: (2025-01-01)

CD11c+ and IRF8+ cell densities in rectal cancer biopsies predict outcomes of neoadjuvant chemoradiotherapy
by: Benita C. Y. Tse, et al.
Published: (2023-12-01)

Multimodality deep learning radiomics predicts pathological response after neoadjuvant chemoradiotherapy for esophageal squamous cell carcinoma
by: Yunsong Liu, et al.
Published: (2024-11-01)

MRI delta radiomics during chemoradiotherapy for prognostication in locally advanced cervical cancer
by: Kari S. Wagner-Larsen, et al.
Published: (2025-01-01)

Prognostic value of preoperative D-dimer to albumin ratio in patients with locally advanced rectal cancer after neoadjuvant chemoradiotherapy
by: Zhen Pan, et al.
Published: (2024-12-01)

Tumor microenvironment remodeling after neoadjuvant chemoradiotherapy in local advanced rectal cancer revealed by single-cell RNA sequencing
by: Wenzhao Su, et al.
Published: (2024-11-01)

Prognostic role of the pathological status following neoadjuvant chemoradiotherapy and surgery in esophageal squamous cell carcinoma
by: Xiaofeng Duan, et al.
Published: (2025-01-01)

Longitudinal dynamic MRI radiomic models for early prediction of prognosis in locally advanced cervical cancer treated with concurrent chemoradiotherapy
by: Chang Cai, et al.
Published: (2024-12-01)

A randomized phase 3 trial of total neoadjuvant therapy (induction chemotherapy, neoadjuvant chemoradiation, neoadjuvant chemotherapy, and surgery) vs. standard long-term chemoradiation therapy (neoadjuvant chemoradiation, surgery, and adjuvant chemotherapy) in locally advanced rectal cancer
by: Freshte Foroughi, et al.
Published: (2024-12-01)

Pathomics-based machine learning models for predicting pathological complete response and prognosis in locally advanced rectal cancer patients post-neoadjuvant chemoradiotherapy: insights from two independent institutional studies
by: Yiyi Zhang, et al.
Published: (2024-12-01)

Computed Tomography Scan and Clinical-based Complete Response Prediction in Locally Advanced Rectal Cancer after Neoadjuvant Chemoradiotherapy: A Machine Learning Approach
by: Seyyed Hossein Mousavie Anijdan, et al.
Published: (2024-12-01)

Radiomics in rectal cancer: current status of use and advances in research
by: Wei-Qin Huang, et al.
Published: (2025-01-01)

Comparison of prognosis for T4b rectal cancer with different pelvic compartment involvement treated using neoadjuvant chemoradiotherapy and implications for refinement of the current T staging system: A retrospective cohort study
by: Yang-zi Zhang, et al.
Published: (2025-03-01)

Total neoadjuvant therapy based on short-course radiotherapy versus standard long-course chemoradiotherapy for locally advanced rectal cancer: a systematic review and meta-analysis of randomized controlled trials
by: Wenji Pu, et al.
Published: (2024-12-01)

Corrigendum: Total neoadjuvant therapy based on short-course radiotherapy versus standard long-course chemoradiotherapy for locally advanced rectal cancer: a systematic review and meta-analysis of randomized controlled trials
by: Wenji Pu, et al.
Published: (2025-01-01)

Hemoglobin Level as a Prognostic Factor of Neoadjuvant Chemoradiotherapy in Patients with Rectal Cancer
by: Berrin Yalçın, et al.
Published: (2024-11-01)

S100A4 contributes to colorectal carcinoma aggressive behavior and to chemoradiotherapy resistance in locally advanced rectal carcinoma
by: Yohei Harada, et al.
Published: (2024-12-01)

Efficacy and safety of neoadjuvant S-1-based chemoradiotherapy in resectable and borderline-resectable pancreatic cancer: a long-term follow-up study
by: Gaku Shimane, et al.
Published: (2024-12-01)

Esophageal squamous cell carcinoma with EP300 mutations displays distinct genetic characteristics relevant to neoadjuvant chemoradiotherapy
by: Yutian Lai, et al.
Published: (2025-01-01)

Rectal Cancer: Exploring Predictive Biomarkers Through Molecular Pathways Involved in Carcinogenesis
by: Sheila Martins, et al.
Published: (2024-12-01)

Characterization and dosimetric predictors for absolute lymphocyte count changes during neoadjuvant chemoradiotherapy with or without pembrolizumab for esophageal squamous cell carcinoma: an analysis of a prospective cohort
by: Wei-Xiang Qi, et al.
Published: (2025-01-01)

Identification of biomarkers for tumor regression grade in esophageal squamous cell carcinoma patients after neoadjuvant chemoradiotherapy
by: Zhifu Chen, et al.
Published: (2025-01-01)

Identification of key genes to predict response to chemoradiotherapy and prognosis in esophageal squamous cell carcinoma
by: Yingying Cui, et al.
Published: (2024-11-01)

CT-based habitat radiomics for predicting treatment response to neoadjuvant chemoimmunotherapy in esophageal cancer patients
by: Weibo Kong, et al.
Published: (2024-12-01)

A Machine Learning Model Based on MRI Radiomics to Predict Response to Chemoradiation Among Patients with Rectal Cancer
by: Filippo Crimì, et al.
Published: (2024-11-01)

Neoadjuvant therapy in rectal cancer—one year follow-up results of standard versus total neoadjuvant strategies
by: Luís Correia Gomes, et al.
Published: (2024-11-01)

Magnetic resonance imaging‐based radiomics nomogram for the evaluation of therapeutic responses to neoadjuvant chemohormonal therapy in high‐risk non‐metastatic prostate cancer
by: Xiao‐Hui Wu, et al.
Published: (2024-07-01)

What is the role of lateral lymph node dissection in rectal cancer patients with clinically suspected lateral lymph node metastasis after preoperative chemoradiotherapy? A meta‐analysis and systematic review
by: Xuyang Yang, et al.
Published: (2020-07-01)

Radiomics of magnetic resonance imaging for assessment of pathological complete response to neoadjuvant therapy and long-term survival in breast cancer
by: N. V. Petrova, et al.
Published: (2023-09-01)

CT-based delta-radiomics for predicting pathological response to neoadjuvant immunochemotherapy in esophageal squamous cell carcinoma: a multicenter study
by: Yuting Zheng, et al.
Published: (2024-12-01)

Definite Treatment Delay With Neoadjuvant Chemotherapy and Longitudinal Monitoring by Circulating Tumor DNA for Advanced Cervical Cancer During Pregnancy: A Case Series and Literature Review
by: Xiaoyu Zhang, et al.
Published: (2024-11-01)

Intravenous versus oral iron supplementation for iron deficiency anemia in patients with rectal cancer undergoing neoadjuvant chemoradiotherapy: a study protocol for a randomized controlled trial
by: Hyeung-min Park, et al.
Published: (2024-11-01)

How Can We Improve the Tumor Response to Preoperative Chemoradiotherapy for Locally Advanced Rectal Cancer?
by: Jeonghee Han
Published: (2023-12-01)

Clinical Implication of Lateral Pelvic Lymph Node Metastasis in Rectal Cancer Treated with Neoadjuvant Chemoradiotherapy
by: In Ja Park
Published: (2022-01-01)

Predictive value of circulating lymphocyte subsets and inflammatory indexes for neoadjuvant chemoradiotherapy response in rectal mucinous adenocarcinoma patients: A machine learning approach
by: Yu Lin, et al.
Published: (2024-07-01)

Combined morphology and radiomics of intravoxel incoherent movement as a predictive model for the pathologic complete response before neoadjuvant chemotherapy in patients with breast cancer
by: Yunyan Zheng, et al.
Published: (2025-02-01)

Prognostic Value of Tumor Regression Grade Combined with Pathological Lymph Node Status in Initially Node-Positive Rectal Cancer Treated with Neoadjuvant Chemoradiotherapy
by: Dakui Luo, et al.
Published: (2025-01-01)

Neoadjuvant chemoradiotherapy up-regulates PD-L1 in radioresistant colorectal cancer
by: Sung Uk Bae, et al.
Published: (2025-03-01)

Combining Endoscopic Submucosal Dissection and Adjuvant Chemoradiotherapy or Radiotherapy for Effective Management of Rectal Cancer with Deep Submucosal Invasion: A Case Series
by: Ji Hye Park, et al.
Published: (2024-11-01)