Differential diagnosis of hematogenous osteomyelitis and malignant bone tumors
The objective of the study was to develop a mathematical model of differential diagnosis of hematogenous osteomyelitis and malignant bone tumor.Material and methods. In this research we performed a retrospective analysis of the data on 127 patients with differential diagnosis between hematogenous os...
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| Format: | Article |
| Language: | Russian |
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Pavlov First Saint Petersburg State Medical University
2018-10-01
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| Series: | Вестник хирургии имени И.И. Грекова |
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| Online Access: | https://www.vestnik-grekova.ru/jour/article/view/1053 |
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| author | A. N. Tkachenko O. F. Nur A. A. Korneenkov L. E. Sharova I. E. Itskovich I. I. Kushnirchuk A. Yu. Cherkasov |
| author_facet | A. N. Tkachenko O. F. Nur A. A. Korneenkov L. E. Sharova I. E. Itskovich I. I. Kushnirchuk A. Yu. Cherkasov |
| author_sort | A. N. Tkachenko |
| collection | DOAJ |
| description | The objective of the study was to develop a mathematical model of differential diagnosis of hematogenous osteomyelitis and malignant bone tumor.Material and methods. In this research we performed a retrospective analysis of the data on 127 patients with differential diagnosis between hematogenous osteomyelitis and malignant bone tumors. Retrospective validity indicators: sensitivity (Se) – 53.12 % (42.66–63.39 %), specificity (Sp) – 70.97 % (51.96–85.78 %). Data on 96 patients with subsequently diagnosed hematogenous osteomyelitis was compared with data on 31 patients with morphologically confirmed malignant bone neoplasms. In the research we.Results. The database was created based on studying the data of the retrospective group. It became the basis for the development of a mathematical model for the differential diagnosis of hematogenous osteomyelitis and malignant bone tumors. 13 prognostic criteria were identified, each of which is quantified. These criteria included the age of the patient, sex, the data on concomitant pathology, information about the localization of the pathological process, the indices of some laboratory studies, etc. An algorithm for the differential diagnosis of hematogenous.Conclusion. Our differential diagnostic model was tested in the prospective study (63 cases). Indicators of the validity of the test was: Sensitivity – 83.05 %, Specificity (Sp) – 86.67 %. Positive Predictive Value (PPV) was 96.08 %, Negative Predictive Value (NPV) – 56.52 %, Accuracy – 83.78 %, which allowed to shorten the time of examination and send patients to specialized hospitals. |
| format | Article |
| id | doaj-art-9c70ea59f0b94984953d67698a0a0087 |
| institution | Kabale University |
| issn | 0042-4625 |
| language | Russian |
| publishDate | 2018-10-01 |
| publisher | Pavlov First Saint Petersburg State Medical University |
| record_format | Article |
| series | Вестник хирургии имени И.И. Грекова |
| spelling | doaj-art-9c70ea59f0b94984953d67698a0a00872024-11-26T10:43:52ZrusPavlov First Saint Petersburg State Medical UniversityВестник хирургии имени И.И. Грекова0042-46252018-10-011775586210.24884/0042-4625-2018-177-5-58-62913Differential diagnosis of hematogenous osteomyelitis and malignant bone tumorsA. N. Tkachenko0O. F. Nur1A. A. Korneenkov2L. E. Sharova3I. E. Itskovich4I. I. Kushnirchuk5A. Yu. Cherkasov6Federal State Budgetary Educational Institution of Higher Education «North-Western State Medical University named after I.I. Mechnikov», of the Ministry of Healthcare of the Russian FederationFederal State Budgetary Educational Institution of Higher Education «North-Western State Medical University named after I.I. Mechnikov», of the Ministry of Healthcare of the Russian FederationFederal State Budgetary Military Educational Institution of Higher Education «Military Medical Academy named after S.M. Kirov» of the Ministry of Defence of the Russian FederationFederal State Budgetary Educational Institution of Higher Education «North-Western State Medical University named after I.I. Mechnikov», of the Ministry of Healthcare of the Russian FederationFederal State Budgetary Educational Institution of Higher Education «North-Western State Medical University named after I.I. Mechnikov», of the Ministry of Healthcare of the Russian FederationFederal State Budgetary Military Educational Institution of Higher Education «Military Medical Academy named after S.M. Kirov» of the Ministry of Defence of the Russian FederationFederal State Budgetary Educational Institution of Higher Education «North-Western State Medical University named after I.I. Mechnikov», of the Ministry of Healthcare of the Russian FederationThe objective of the study was to develop a mathematical model of differential diagnosis of hematogenous osteomyelitis and malignant bone tumor.Material and methods. In this research we performed a retrospective analysis of the data on 127 patients with differential diagnosis between hematogenous osteomyelitis and malignant bone tumors. Retrospective validity indicators: sensitivity (Se) – 53.12 % (42.66–63.39 %), specificity (Sp) – 70.97 % (51.96–85.78 %). Data on 96 patients with subsequently diagnosed hematogenous osteomyelitis was compared with data on 31 patients with morphologically confirmed malignant bone neoplasms. In the research we.Results. The database was created based on studying the data of the retrospective group. It became the basis for the development of a mathematical model for the differential diagnosis of hematogenous osteomyelitis and malignant bone tumors. 13 prognostic criteria were identified, each of which is quantified. These criteria included the age of the patient, sex, the data on concomitant pathology, information about the localization of the pathological process, the indices of some laboratory studies, etc. An algorithm for the differential diagnosis of hematogenous.Conclusion. Our differential diagnostic model was tested in the prospective study (63 cases). Indicators of the validity of the test was: Sensitivity – 83.05 %, Specificity (Sp) – 86.67 %. Positive Predictive Value (PPV) was 96.08 %, Negative Predictive Value (NPV) – 56.52 %, Accuracy – 83.78 %, which allowed to shorten the time of examination and send patients to specialized hospitals.https://www.vestnik-grekova.ru/jour/article/view/1053hematogenous osteomyelitismalignant bone tumordifferential diagnosis |
| spellingShingle | A. N. Tkachenko O. F. Nur A. A. Korneenkov L. E. Sharova I. E. Itskovich I. I. Kushnirchuk A. Yu. Cherkasov Differential diagnosis of hematogenous osteomyelitis and malignant bone tumors Вестник хирургии имени И.И. Грекова hematogenous osteomyelitis malignant bone tumor differential diagnosis |
| title | Differential diagnosis of hematogenous osteomyelitis and malignant bone tumors |
| title_full | Differential diagnosis of hematogenous osteomyelitis and malignant bone tumors |
| title_fullStr | Differential diagnosis of hematogenous osteomyelitis and malignant bone tumors |
| title_full_unstemmed | Differential diagnosis of hematogenous osteomyelitis and malignant bone tumors |
| title_short | Differential diagnosis of hematogenous osteomyelitis and malignant bone tumors |
| title_sort | differential diagnosis of hematogenous osteomyelitis and malignant bone tumors |
| topic | hematogenous osteomyelitis malignant bone tumor differential diagnosis |
| url | https://www.vestnik-grekova.ru/jour/article/view/1053 |
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