A deep ensemble framework for human essential gene prediction by integrating multi-omics data

Abstract Essential genes are necessary for the survival or reproduction of a living organism. The prediction and analysis of gene essentiality can advance our understanding of basic life and human diseases, and further boost the development of new drugs. We propose a snapshot ensemble deep neural ne...

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Bibliographic Details
Main Authors: Xue Zhang, Weijia Xiao, Brent Cochran, Wangxin Xiao
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-99164-9
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