Loading monocytes with magnetic nanoparticles enables their magnetic control without toxicity

Loading monocytes with magnetic nanoparticles enables their magnetic control without toxicity

BackgroundWith the help of superparamagnetic iron oxide nanoparticles (SPIONs), cells can be magnetically directed so that they can be accumulated at target sites. This principle can be used to make monocytes magnetically steerable in order to improve tumor accumulation, e.g., for immunotherapy with...

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Bibliographic Details
Main Authors: Laura Mödl, Lucas R. Carnell, Rene Stein, Andrea Kerpes, Felix Pfister, Barbara Wirthl, Wolfgang A. Wall, Christoph Alexiou, Christina Janko
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
iron oxide nanoparticles
computer simulation
magnetic cell targeting
nanomedicine
solid cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2024.1498120/full
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