Antibacterial properties of the aqueous extract of Hypericum coris and relative purification of its antibacterial compounds
Introduction: Hypericum coris is used in western Iran for wound disinfection. This study aimed to investigate the antibacterial properties of the aqueous extract of this plant against certain pathogenic bacteria and to purify its antibacterial compounds partially. Materials & Methods: The aeria...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | fas |
| Published: |
Ilam University of Medical Sciences
2025-07-01
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| Series: | Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām |
| Subjects: | |
| Online Access: | http://sjimu.medilam.ac.ir/article-1-8512-en.pdf |
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| Summary: | Introduction: Hypericum coris is used in western Iran for wound disinfection. This study aimed to investigate the antibacterial properties of the aqueous extract of this plant against certain pathogenic bacteria and to purify its antibacterial compounds partially.
Materials & Methods: The aerial parts of the plant were extracted using maceration. The antibacterial characteristics of the extract were evaluated against common wound infection-causing bacteria using disk diffusion and MIC. To partially purify the antibacterial compounds, the extract was subjected to various solvents, and each fraction was assessed for its antibacterial properties. Data analysis was conducted using one-way analysis of variance (ANOVA), and means were compared using Duncan's multiple range test. It was performed using SPSS V.18 at a significance level (p≥0.05).
Results: The findings indicated that the aqueous extract was effective against all the studied bacteria, with a greater impact on Gram-positive bacteria. It was also determined that only the polar fractions have antibacterial activity, and their antibacterial potency increased as polarity increased.
Conclusion: This was the first report on the effects of the aqueous extract of H. coris on pathogenic bacteria, demonstrating that this extract is effective against all studied bacterial strains. Additionally, it was found that the antibacterial compounds present in the extract are polar. |
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| ISSN: | 1563-4728 2588-3135 |