Clinical characterization of CCT2 and its role in autophagy regulation during age-related macular degeneration

Clinical characterization of CCT2 and its role in autophagy regulation during age-related macular degeneration

Abstract Age-related macular degeneration (AMD) is the leading cause of vision loss in the elderly, and the role of chaperonin containing TCP1 subunit 2 (CCT2) remains unclear. This study aims to elucidate the mechanistic link between CCT2 and AMD, contributing to improved understanding and potentia...

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Bibliographic Details
Main Authors: Lin Wang, Ling-xiao Wang, Mu-ye Li, Rong Zhang, Guo-hong Zhou
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Age related macular degeneration
Neurodegeneration
CCT2
Autophagy
Drusen
Online Access:https://doi.org/10.1038/s41598-025-01907-1
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