LGR6 protects against myocardial ischemia-reperfusion injury via suppressing necroptosis

LGR6 protects against myocardial ischemia-reperfusion injury via suppressing necroptosis

Regulated necrosis (necroptosis) and apoptosis are important biological features of ischemia-reperfusion (I/R) injury. However, the molecular mechanisms underlying myocardial necroptosis remain elusive. Leucine rich repeat containing G protein-coupled receptor 6 (LGR6) has been reported to play impo...

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Bibliographic Details
Main Authors: Mengmeng Zhao, Zihui Zheng, Jianfang Liu, Yao Xu, Jishou Zhang, Shanshan Peng, Juan-Juan Qin, Jun Wan, Menglong Wang
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Redox Biology
Subjects:
LGR6
Necroptosis
ZBP1
STAT2
Myocardial ischemia-reperfusion injury
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231724003781
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