An Interesting Case of Kidney Transplant Recipient with Multiple Concomitant Infections- 10 Years Post Transplantation
Opportunistic infections or pathogens that reactivate from latent infection in the renal transplant recipients often arise during the peak immunosuppression period and infections such as Pneumocystis jirovecii may arise in the late period of posttransplant. In developing countries, tuberculosis (TB)...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Indian Journal of Transplantation |
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| Online Access: | https://journals.lww.com/10.4103/ijot.ijot_10_23 |
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| author | Chilaka Rajesh Utkarsh Mishra Ankit Jain T. Jayaprakash Phaneesh Bharadwaj Selvin Sundar Rajmani Nisha Jose Jeethu Joseph Eapen Elenjickal Elias John Santosh Varughese |
| author_facet | Chilaka Rajesh Utkarsh Mishra Ankit Jain T. Jayaprakash Phaneesh Bharadwaj Selvin Sundar Rajmani Nisha Jose Jeethu Joseph Eapen Elenjickal Elias John Santosh Varughese |
| author_sort | Chilaka Rajesh |
| collection | DOAJ |
| description | Opportunistic infections or pathogens that reactivate from latent infection in the renal transplant recipients often arise during the peak immunosuppression period and infections such as Pneumocystis jirovecii may arise in the late period of posttransplant. In developing countries, tuberculosis (TB) is a major concern among transplant patients. Here, we present a case of 42-year-old male who presented after 10 years of renal transplant with a history of fever. On evaluation, he was diagnosed to have concomitant multiple infections like disseminated TB, Cryptococcal meningitis, Cytomegalovirus viremia, and Pneumocystis infection. He was treated with appropriate antibiotics, antifungal, and antiviral with close monitoring of drug-related side effects and graft function. Detailed evaluation and to look for concomitant infections is required for transplant patients who had no response to one particular group of drugs after initial diagnosis. He had stable graft function and developed drug-related side effects which required dose reduction intermittently. This case taught us how to manage four major infections with balancing immunosuppression, antibiotics, and graft function that we see in day-to-day practice of transplant clinics. |
| format | Article |
| id | doaj-art-9b628b55a7514e7ea1ca40bb83ff4521 |
| institution | Kabale University |
| issn | 2212-0017 2212-0025 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Transplantation |
| spelling | doaj-art-9b628b55a7514e7ea1ca40bb83ff45212025-01-07T06:12:53ZengWolters Kluwer Medknow PublicationsIndian Journal of Transplantation2212-00172212-00252024-12-0118444945210.4103/ijot.ijot_10_23An Interesting Case of Kidney Transplant Recipient with Multiple Concomitant Infections- 10 Years Post TransplantationChilaka RajeshUtkarsh MishraAnkit JainT. JayaprakashPhaneesh BharadwajSelvin Sundar RajmaniNisha JoseJeethu Joseph EapenElenjickal Elias JohnSantosh VarugheseOpportunistic infections or pathogens that reactivate from latent infection in the renal transplant recipients often arise during the peak immunosuppression period and infections such as Pneumocystis jirovecii may arise in the late period of posttransplant. In developing countries, tuberculosis (TB) is a major concern among transplant patients. Here, we present a case of 42-year-old male who presented after 10 years of renal transplant with a history of fever. On evaluation, he was diagnosed to have concomitant multiple infections like disseminated TB, Cryptococcal meningitis, Cytomegalovirus viremia, and Pneumocystis infection. He was treated with appropriate antibiotics, antifungal, and antiviral with close monitoring of drug-related side effects and graft function. Detailed evaluation and to look for concomitant infections is required for transplant patients who had no response to one particular group of drugs after initial diagnosis. He had stable graft function and developed drug-related side effects which required dose reduction intermittently. This case taught us how to manage four major infections with balancing immunosuppression, antibiotics, and graft function that we see in day-to-day practice of transplant clinics.https://journals.lww.com/10.4103/ijot.ijot_10_23cytomegalovirus viraemiacryptococcal meningitisdisseminated tuberculosis |
| spellingShingle | Chilaka Rajesh Utkarsh Mishra Ankit Jain T. Jayaprakash Phaneesh Bharadwaj Selvin Sundar Rajmani Nisha Jose Jeethu Joseph Eapen Elenjickal Elias John Santosh Varughese An Interesting Case of Kidney Transplant Recipient with Multiple Concomitant Infections- 10 Years Post Transplantation Indian Journal of Transplantation cytomegalovirus viraemia cryptococcal meningitis disseminated tuberculosis |
| title | An Interesting Case of Kidney Transplant Recipient with Multiple Concomitant Infections- 10 Years Post Transplantation |
| title_full | An Interesting Case of Kidney Transplant Recipient with Multiple Concomitant Infections- 10 Years Post Transplantation |
| title_fullStr | An Interesting Case of Kidney Transplant Recipient with Multiple Concomitant Infections- 10 Years Post Transplantation |
| title_full_unstemmed | An Interesting Case of Kidney Transplant Recipient with Multiple Concomitant Infections- 10 Years Post Transplantation |
| title_short | An Interesting Case of Kidney Transplant Recipient with Multiple Concomitant Infections- 10 Years Post Transplantation |
| title_sort | interesting case of kidney transplant recipient with multiple concomitant infections 10 years post transplantation |
| topic | cytomegalovirus viraemia cryptococcal meningitis disseminated tuberculosis |
| url | https://journals.lww.com/10.4103/ijot.ijot_10_23 |
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