The optimization and application of photodynamic diagnosis and autofluorescence imaging in tumor diagnosis and guided surgery: current status and future prospects
Photodynamic diagnosis (PDD) and autofluorescence imaging (AFI) are emerging cancer diagnostic technologies that offer significant advantages over traditional white-light endoscopy in detecting precancerous lesions and early-stage cancers; moreover, they hold promising potential in fluorescence-guid...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2024.1503404/full |
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| author | Wei Wan Huiquan Liu Junrong Zou Tianpeng Xie Guoxi Zhang Weihai Ying Xiaofeng Zou Xiaofeng Zou Xiaofeng Zou |
| author_facet | Wei Wan Huiquan Liu Junrong Zou Tianpeng Xie Guoxi Zhang Weihai Ying Xiaofeng Zou Xiaofeng Zou Xiaofeng Zou |
| author_sort | Wei Wan |
| collection | DOAJ |
| description | Photodynamic diagnosis (PDD) and autofluorescence imaging (AFI) are emerging cancer diagnostic technologies that offer significant advantages over traditional white-light endoscopy in detecting precancerous lesions and early-stage cancers; moreover, they hold promising potential in fluorescence-guided surgery (FGS) for tumors. However, their shortcomings have somewhat hindered the clinical application of PDD and AFI. Therefore, it is imperative to enhance the efficacy of PDD and AFI, thereby maximizing their potential for practical clinical use. This article reviews the principles, characteristics, current research status, and advancements of PDD and AFI, focusing on analyzing and discussing the optimization strategies of PDD and AFI in tumor diagnosis and FGS scenarios. Considering the practical and technical feasibility, optimizing PDD and AFI may result in an effective real-time diagnostic tool to guide clinicians in tumor diagnosis and surgical guidance to achieve the best results. |
| format | Article |
| id | doaj-art-9b11dd0c651843498d27cb372b37492d |
| institution | Kabale University |
| issn | 2234-943X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj-art-9b11dd0c651843498d27cb372b37492d2025-01-08T05:10:26ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-01-011410.3389/fonc.2024.15034041503404The optimization and application of photodynamic diagnosis and autofluorescence imaging in tumor diagnosis and guided surgery: current status and future prospectsWei Wan0Huiquan Liu1Junrong Zou2Tianpeng Xie3Guoxi Zhang4Weihai Ying5Xiaofeng Zou6Xiaofeng Zou7Xiaofeng Zou8The First Clinical College, Gannan Medical University, Ganzhou, Jiangxi, ChinaThe First Clinical College, Gannan Medical University, Ganzhou, Jiangxi, ChinaInstitute of Urology, The First Affiliated Hospital of Gannan Medical University, Ganzhou, ChinaDepartment of Urology, The First Affiliated Hospital of Gannan Medical University, Ganzhou, ChinaDepartment of Urology, The First Affiliated Hospital of Gannan Medical University, Ganzhou, ChinaSchool of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, ChinaThe First Clinical College, Gannan Medical University, Ganzhou, Jiangxi, ChinaInstitute of Urology, The First Affiliated Hospital of Gannan Medical University, Ganzhou, ChinaDepartment of Urology, The First Affiliated Hospital of Gannan Medical University, Ganzhou, ChinaPhotodynamic diagnosis (PDD) and autofluorescence imaging (AFI) are emerging cancer diagnostic technologies that offer significant advantages over traditional white-light endoscopy in detecting precancerous lesions and early-stage cancers; moreover, they hold promising potential in fluorescence-guided surgery (FGS) for tumors. However, their shortcomings have somewhat hindered the clinical application of PDD and AFI. Therefore, it is imperative to enhance the efficacy of PDD and AFI, thereby maximizing their potential for practical clinical use. This article reviews the principles, characteristics, current research status, and advancements of PDD and AFI, focusing on analyzing and discussing the optimization strategies of PDD and AFI in tumor diagnosis and FGS scenarios. Considering the practical and technical feasibility, optimizing PDD and AFI may result in an effective real-time diagnostic tool to guide clinicians in tumor diagnosis and surgical guidance to achieve the best results.https://www.frontiersin.org/articles/10.3389/fonc.2024.1503404/fullphotodynamic diagnosisautofluorescence imagingphotosensitizertumorfluorescence-guided surgerydiagnosis |
| spellingShingle | Wei Wan Huiquan Liu Junrong Zou Tianpeng Xie Guoxi Zhang Weihai Ying Xiaofeng Zou Xiaofeng Zou Xiaofeng Zou The optimization and application of photodynamic diagnosis and autofluorescence imaging in tumor diagnosis and guided surgery: current status and future prospects Frontiers in Oncology photodynamic diagnosis autofluorescence imaging photosensitizer tumor fluorescence-guided surgery diagnosis |
| title | The optimization and application of photodynamic diagnosis and autofluorescence imaging in tumor diagnosis and guided surgery: current status and future prospects |
| title_full | The optimization and application of photodynamic diagnosis and autofluorescence imaging in tumor diagnosis and guided surgery: current status and future prospects |
| title_fullStr | The optimization and application of photodynamic diagnosis and autofluorescence imaging in tumor diagnosis and guided surgery: current status and future prospects |
| title_full_unstemmed | The optimization and application of photodynamic diagnosis and autofluorescence imaging in tumor diagnosis and guided surgery: current status and future prospects |
| title_short | The optimization and application of photodynamic diagnosis and autofluorescence imaging in tumor diagnosis and guided surgery: current status and future prospects |
| title_sort | optimization and application of photodynamic diagnosis and autofluorescence imaging in tumor diagnosis and guided surgery current status and future prospects |
| topic | photodynamic diagnosis autofluorescence imaging photosensitizer tumor fluorescence-guided surgery diagnosis |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2024.1503404/full |
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