NKX6.3 modulation of mitotic dynamics and genomic stability in gastric carcinogenesis

NKX6.3 modulation of mitotic dynamics and genomic stability in gastric carcinogenesis

Abstract Background Gastric cancer remains a significant global health challenge, characterized by poor prognosis and high mortality rates. Mitotic integrity and genomic stability are crucial in maintaining cellular homeostasis and preventing tumorigenesis. The transcription factor NKX6.3 has emerge...

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Bibliographic Details
Main Authors: Jung Hwan Yoon, Jeong-Kyu Kim, Jung Woo Eun, Hassan Ashktorab, Duane T. Smoot, Suk Woo Nam, Won Sang Park
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Cell Communication and Signaling
Subjects:
NKX6.3
Mitotic integrity
Genomic stability
Gastric carcinogenesis
Online Access:https://doi.org/10.1186/s12964-025-02030-4
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