Histopathological analysis of duragen collagen matrix over time in humans

Histopathological analysis of duragen collagen matrix over time in humans

Abstract DuraGen is a widely used type I collagen matrix derived from bovine Achilles tendon that promotes fibroblast ingrowth and neovascularization. However, it remains unknown the time required for dura regeneration and reabsorption of the graft. We evaluate the histopathological characteristics...

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Bibliographic Details
Main Authors: Takuma Maeda, Kaima Suzuki, Peyton L. Nisson, Yoshiki Mochizuki, Reina Mizuno, Akio Teranishi, Yushiro Take, Tomomichi Kayahara, Hiroki Kurita
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Collagen matrix
Cranioplasty
DuraGen
Dural regeneration
Endogenous collagen
Fibroblast
Online Access:https://doi.org/10.1038/s41598-025-95489-7
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