The two-component system ArlRS is essential for wall teichoic acid glycoswitching in Staphylococcus aureus

The two-component system ArlRS is essential for wall teichoic acid glycoswitching in Staphylococcus aureus

ABSTRACT Staphylococcus aureus is among the leading causes of hospital-acquired infections. Critical to S. aureus biology and pathogenesis are the cell wall-anchored glycopolymers wall teichoic acids (WTA). Approximately one-third of S. aureus isolates decorates WTA with a mixture of α1,4- and β1,4-...

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Bibliographic Details
Main Authors: Marieke M. Kuijk, Emma Tusveld, Esther Lehmann, Rob van Dalen, Iñigo Lasa, Hanne Ingmer, Yvonne Pannekoek, Nina M. van Sorge
Format: Article
Language:English
Published: American Society for Microbiology 2025-01-01
Series:mBio
Subjects:
Staphylococcus aureus
wall teichoic acid
glycosylation
host-pathogen interactions
virulence regulation
two-component regulatory systems
Online Access:https://journals.asm.org/doi/10.1128/mbio.02668-24
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