Immunogenicity of GamLPV, an intranasal live vaccine for pertussis prevention, in adult volunteers: a blind, randomised, placebo-controlled trial to optimise the method and schedule of administration

Immunogenicity of GamLPV, an intranasal live vaccine for pertussis prevention, in adult volunteers: a blind, randomised, placebo-controlled trial to optimise the method and schedule of administration

INTRODUCTION. Currently used inactivated vaccines with acellular/whole-cell pertussis components do not provide sterilising or sufficiently long-lasting immunity, nor do these vaccines prevent the spread of the pathogen or infection. A live pertussis vaccine for intranasal administration, GamLPV, ha...

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Main Authors: A. A. Lidzhieva, A. Yu. Medkova, S. V. Kulikov, L. N. Sinyashina, R. A. Sioundioukova, I. N. Chernyshova, M. V. Gavrilova, K. K. Bushkova, N. A. Snegireva, I. N. Dyakov, G. I. Karataev
Format: Article
Language:Russian
Published: Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2025-04-01
Series:Биопрепараты: Профилактика, диагностика, лечение
Subjects:
pertussis
live pertussis vaccine
intranasal administration
method of administration
vaccination schedule
volunteers
immunogenicity
antibacterial immunity
bordetella pertussis
Online Access:https://www.biopreparations.ru/jour/article/view/610
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