Shionone Inhibits Glomerular Fibirosis by Suppressing NLRP3 Related Inflammasome though SESN2-NRF2/HO-1 Pathway

Shionone Inhibits Glomerular Fibirosis by Suppressing NLRP3 Related Inflammasome though SESN2-NRF2/HO-1 Pathway

Background Diabetic nephropathy (DN) is the most common and serious complication of diabetes mellitus. Shionone (SH), an important triterpenoid compound in the root extract of Aster, might exert a protective effect in DN mice and high glucose cultivated glomerular podocytes. The current study aimed...

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Bibliographic Details
Main Authors:	Tian Xiao, Hanzhen Zhao, Yucong Wang, Mengyin Chen, Cong Wang, Chen Qiao
Format:	Article
Language:	English
Published:	Korean Diabetes Association 2025-01-01
Series:	Diabetes & Metabolism Journal
Subjects:	nlr family, pyrin domain-containing 3 protein sesn 2 protein shionone
Online Access:	http://e-dmj.org/upload/pdf/dmj-2024-0024.pdf
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