Effects of milk powder fortified with red ginseng extracts on the skin barrier function and immunity of middle-aged women
This study investigated the effects of a nutritional milk composition containing red ginseng extract (MCCRG) on the skin barrier function and immunity of middle-aged women. Fifty women (aged, 25 to 45) consumed MCCRG orally for 56 days. Evaluations of skin phenotype, facial bacterial microbiome, imm...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-12-01
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| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464624006169 |
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| author | Yao Ge Wenhui Ye Yue Wang Aiqin Ma Man Wang Qingshan Chen Xiaoyan Huo Chunxi Liu Yujie Shi Biao Liu Wei Chen |
| author_facet | Yao Ge Wenhui Ye Yue Wang Aiqin Ma Man Wang Qingshan Chen Xiaoyan Huo Chunxi Liu Yujie Shi Biao Liu Wei Chen |
| author_sort | Yao Ge |
| collection | DOAJ |
| description | This study investigated the effects of a nutritional milk composition containing red ginseng extract (MCCRG) on the skin barrier function and immunity of middle-aged women. Fifty women (aged, 25 to 45) consumed MCCRG orally for 56 days. Evaluations of skin phenotype, facial bacterial microbiome, immune system function, and clinical diagnoses were conducted. The results indicated that MCCRG significantly improved skin hydration, firmness, elasticity, and glossiness. Furthermore, MCCRG also reduced TEWL and wrinkles and enhanced skin barrier integrity. Additionally, high IgG levels and improved CD4+/CD8+ ratios due to MCCRG consumption increased facial microbiota diversity and immune function. Clinical diagnoses provided supplementary evidence for the efficacy of MCCRG. The findings of this study demonstrated that MCCRG, through nutritional support, enhanced both skin barrier and immune system functions. This study offers substantial evidence of the innovative therapeutic effects of nutritional support on skin barrier damage and immune function. |
| format | Article |
| id | doaj-art-9a7a8de0ba034abe818d64dd1c619ae0 |
| institution | Kabale University |
| issn | 1756-4646 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Functional Foods |
| spelling | doaj-art-9a7a8de0ba034abe818d64dd1c619ae02024-12-14T06:30:22ZengElsevierJournal of Functional Foods1756-46462024-12-01123106613Effects of milk powder fortified with red ginseng extracts on the skin barrier function and immunity of middle-aged womenYao Ge0Wenhui Ye1Yue Wang2Aiqin Ma3Man Wang4Qingshan Chen5Xiaoyan Huo6Chunxi Liu7Yujie Shi8Biao Liu9Wei Chen10Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai,PR ChinaJinshan Branch Company, Inner Mongolia Yili Industrial Group Co.,Ltd.,Hohhot, PR ChinaShanghai Institute of Technology,Shanghai,PR ChinaShanghai Jiao Tong University Affiliated Sixth People's Hospital South Campus,Shanghai,PR ChinaShanghai Jiao Tong University Affiliated Sixth People's Hospital South Campus,Shanghai,PR ChinaJinshan Branch Company, Inner Mongolia Yili Industrial Group Co.,Ltd.,Hohhot, PR ChinaJinshan Branch Company, Inner Mongolia Yili Industrial Group Co.,Ltd.,Hohhot, PR ChinaJinshan Branch Company, Inner Mongolia Yili Industrial Group Co.,Ltd.,Hohhot, PR ChinaJinshan Branch Company, Inner Mongolia Yili Industrial Group Co.,Ltd.,Hohhot, PR China; Corresponding authors.Jinshan Branch Company, Inner Mongolia Yili Industrial Group Co.,Ltd.,Hohhot, PR China; Corresponding authors.Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai,PR China; Corresponding authors.This study investigated the effects of a nutritional milk composition containing red ginseng extract (MCCRG) on the skin barrier function and immunity of middle-aged women. Fifty women (aged, 25 to 45) consumed MCCRG orally for 56 days. Evaluations of skin phenotype, facial bacterial microbiome, immune system function, and clinical diagnoses were conducted. The results indicated that MCCRG significantly improved skin hydration, firmness, elasticity, and glossiness. Furthermore, MCCRG also reduced TEWL and wrinkles and enhanced skin barrier integrity. Additionally, high IgG levels and improved CD4+/CD8+ ratios due to MCCRG consumption increased facial microbiota diversity and immune function. Clinical diagnoses provided supplementary evidence for the efficacy of MCCRG. The findings of this study demonstrated that MCCRG, through nutritional support, enhanced both skin barrier and immune system functions. This study offers substantial evidence of the innovative therapeutic effects of nutritional support on skin barrier damage and immune function.http://www.sciencedirect.com/science/article/pii/S1756464624006169NutritionSkin phenotypeSkin barrierSkin microbiomeImmunity |
| spellingShingle | Yao Ge Wenhui Ye Yue Wang Aiqin Ma Man Wang Qingshan Chen Xiaoyan Huo Chunxi Liu Yujie Shi Biao Liu Wei Chen Effects of milk powder fortified with red ginseng extracts on the skin barrier function and immunity of middle-aged women Journal of Functional Foods Nutrition Skin phenotype Skin barrier Skin microbiome Immunity |
| title | Effects of milk powder fortified with red ginseng extracts on the skin barrier function and immunity of middle-aged women |
| title_full | Effects of milk powder fortified with red ginseng extracts on the skin barrier function and immunity of middle-aged women |
| title_fullStr | Effects of milk powder fortified with red ginseng extracts on the skin barrier function and immunity of middle-aged women |
| title_full_unstemmed | Effects of milk powder fortified with red ginseng extracts on the skin barrier function and immunity of middle-aged women |
| title_short | Effects of milk powder fortified with red ginseng extracts on the skin barrier function and immunity of middle-aged women |
| title_sort | effects of milk powder fortified with red ginseng extracts on the skin barrier function and immunity of middle aged women |
| topic | Nutrition Skin phenotype Skin barrier Skin microbiome Immunity |
| url | http://www.sciencedirect.com/science/article/pii/S1756464624006169 |
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