Left Ventricular Apical Aneurysm in a Dog—A Case Report
The cadaver of a 16-year-old mixed-breed male dog was presented to the Faculty of Veterinary Medicine of IULS, Romania, after having been euthanized in a private practice at the owner’s request following acute cardio-respiratory failure. The necropsy revealed a left ventricular apical aneurysm with...
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| Language: | English |
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MDPI AG
2024-11-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/14/23/3412 |
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| author | Ozana Maria Hritcu Radu Andrei Baisan Aurelian Sorin Pasca Florentina Daraban Bocaneti |
| author_facet | Ozana Maria Hritcu Radu Andrei Baisan Aurelian Sorin Pasca Florentina Daraban Bocaneti |
| author_sort | Ozana Maria Hritcu |
| collection | DOAJ |
| description | The cadaver of a 16-year-old mixed-breed male dog was presented to the Faculty of Veterinary Medicine of IULS, Romania, after having been euthanized in a private practice at the owner’s request following acute cardio-respiratory failure. The necropsy revealed a left ventricular apical aneurysm with a bulging fibrous sac measuring about 0.7 cm/0.3 cm. The lesion involved all three structures of the cardiac wall, with mineralization areas and neovascularization. Immunohistochemistry showed strong positivity for desmin and weak positivity for CD-31 in the cardiac muscle fibers, positivity for α-sma in the smooth muscle cells of the vascular walls and positivity for vimentin in the cardiac stroma. MMP-2 and MMP-9 showed strong expression in the cardiomyocytes, whereas TIMP-1 showed positive immunoexpression only in the Eberth’s lines. To the authors’ knowledge, left ventricular apical aneurysm has only been reported once in dogs. |
| format | Article |
| id | doaj-art-9a6e19d43c3c4f09906af70455a1d881 |
| institution | Kabale University |
| issn | 2076-2615 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj-art-9a6e19d43c3c4f09906af70455a1d8812024-12-13T16:21:06ZengMDPI AGAnimals2076-26152024-11-011423341210.3390/ani14233412Left Ventricular Apical Aneurysm in a Dog—A Case ReportOzana Maria Hritcu0Radu Andrei Baisan1Aurelian Sorin Pasca2Florentina Daraban Bocaneti3Faculty of Veterinary Medicine, Iasi University of Life Sciences Ion Ionescu de la Brad, 700489 Iasi, RomaniaFaculty of Veterinary Medicine, Iasi University of Life Sciences Ion Ionescu de la Brad, 700489 Iasi, RomaniaFaculty of Veterinary Medicine, Iasi University of Life Sciences Ion Ionescu de la Brad, 700489 Iasi, RomaniaFaculty of Veterinary Medicine, Iasi University of Life Sciences Ion Ionescu de la Brad, 700489 Iasi, RomaniaThe cadaver of a 16-year-old mixed-breed male dog was presented to the Faculty of Veterinary Medicine of IULS, Romania, after having been euthanized in a private practice at the owner’s request following acute cardio-respiratory failure. The necropsy revealed a left ventricular apical aneurysm with a bulging fibrous sac measuring about 0.7 cm/0.3 cm. The lesion involved all three structures of the cardiac wall, with mineralization areas and neovascularization. Immunohistochemistry showed strong positivity for desmin and weak positivity for CD-31 in the cardiac muscle fibers, positivity for α-sma in the smooth muscle cells of the vascular walls and positivity for vimentin in the cardiac stroma. MMP-2 and MMP-9 showed strong expression in the cardiomyocytes, whereas TIMP-1 showed positive immunoexpression only in the Eberth’s lines. To the authors’ knowledge, left ventricular apical aneurysm has only been reported once in dogs.https://www.mdpi.com/2076-2615/14/23/3412aneurysmdogheartapical |
| spellingShingle | Ozana Maria Hritcu Radu Andrei Baisan Aurelian Sorin Pasca Florentina Daraban Bocaneti Left Ventricular Apical Aneurysm in a Dog—A Case Report Animals aneurysm dog heart apical |
| title | Left Ventricular Apical Aneurysm in a Dog—A Case Report |
| title_full | Left Ventricular Apical Aneurysm in a Dog—A Case Report |
| title_fullStr | Left Ventricular Apical Aneurysm in a Dog—A Case Report |
| title_full_unstemmed | Left Ventricular Apical Aneurysm in a Dog—A Case Report |
| title_short | Left Ventricular Apical Aneurysm in a Dog—A Case Report |
| title_sort | left ventricular apical aneurysm in a dog a case report |
| topic | aneurysm dog heart apical |
| url | https://www.mdpi.com/2076-2615/14/23/3412 |
| work_keys_str_mv | AT ozanamariahritcu leftventricularapicalaneurysminadogacasereport AT raduandreibaisan leftventricularapicalaneurysminadogacasereport AT aureliansorinpasca leftventricularapicalaneurysminadogacasereport AT florentinadarabanbocaneti leftventricularapicalaneurysminadogacasereport |