Fate erasure logic of gene networks underlying direct neuronal conversion of somatic cells by microRNAs
Summary: Neurogenic microRNAs 9/9∗ and 124 (miR-9/9∗-124) drive the direct reprogramming of human fibroblasts into neurons with the initiation of the fate erasure of fibroblasts. However, whether the miR-9/9∗-124 fate erasure logic extends to the neuronal conversion of other somatic cell types remai...
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Main Authors: | Kitra Cates, Luorongxin Yuan, Yan Yang, Andrew S. Yoo |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-01-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124724015043 |
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