Total endovascular arch repair: Initial experience in BolognaCentral MessagePerspective

Objectives: In the last few years, fenestrated, branched, or scalloped custom grafts have become available for aortic arch repair. Open surgery is the gold standard, but arch thoracic endovascular aortic repair (TEVAR) is indicated for high-risk patients. We focused on total endovascular aortic arch...

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Main Authors: Luca Di Marco, MD, PhD, Chiara Nocera, MD, PhD, Francesco Buia, MD, Francesco Campanini, MD, Domenico Attinà, MD, Giacomo Murana, MD, Luigi Lovato, MD, Davide Pacini, MD, PhD
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:JTCVS Techniques
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666250724003602
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author Luca Di Marco, MD, PhD
Chiara Nocera, MD, PhD
Francesco Buia, MD
Francesco Campanini, MD
Domenico Attinà, MD
Giacomo Murana, MD
Luigi Lovato, MD
Davide Pacini, MD, PhD
author_facet Luca Di Marco, MD, PhD
Chiara Nocera, MD, PhD
Francesco Buia, MD
Francesco Campanini, MD
Domenico Attinà, MD
Giacomo Murana, MD
Luigi Lovato, MD
Davide Pacini, MD, PhD
author_sort Luca Di Marco, MD, PhD
collection DOAJ
description Objectives: In the last few years, fenestrated, branched, or scalloped custom grafts have become available for aortic arch repair. Open surgery is the gold standard, but arch thoracic endovascular aortic repair (TEVAR) is indicated for high-risk patients. We focused on total endovascular aortic arch replacement with a zone 0 or zone 1 landing zone to describe its short- and long-term outcomes. Methods: We retrospectively analyzed patients who underwent arch TEVAR with a zone 0 or zone 1 landing zone at our center. We then performed a Kaplan-Meier analysis for survival and freedom from reintervention at follow-up. Results: From May 2017 to November 2023, 15 patients underwent elective arch TEVAR, having been deemed unfit for open surgery. Mean age was 74.7 ± 7.8 years. The most frequent procedure was fenestrated endovascular aortic repair with a left carotid-subclavian bypass (LCSB) (6; 40%), followed by double-branched graft with LCSB (5; 33.3%) and triple-branched graft (2; 13.3%) and scalloped graft with LCSB (2; 13.3%). There was 1 in-hospital death (6.7%). Perioperative stroke occurred in 2 cases (13.3%). Mean follow-up (FU) time was 16.4 ± 15.1 months. There were 3 deaths at FU, all for noncardiovascular causes, and 1 stroke at FU. One patient required further stenting of the brachiocephalic trunk for a type III endoleak. Survival at 12 months was 87.5% and freedom from reintervention was 85.7%. Conclusions: Total endovascular aortic arch repair with custom-made prosthesis is a safe and effective procedure in patients with prohibitive surgical risk. Stroke remains the main complication with significant rates.
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spelling doaj-art-9a3367fc5a0b47d9b10a28ac3ab5b5882025-08-20T03:38:26ZengElsevierJTCVS Techniques2666-25072024-12-01281710.1016/j.xjtc.2024.08.025Total endovascular arch repair: Initial experience in BolognaCentral MessagePerspectiveLuca Di Marco, MD, PhD0Chiara Nocera, MD, PhD1Francesco Buia, MD2Francesco Campanini, MD3Domenico Attinà, MD4Giacomo Murana, MD5Luigi Lovato, MD6Davide Pacini, MD, PhD7Cardiac Surgery Unit, Department of Medical and Surgical Sciences, DIMEC, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Department of Medical and Surgical Sciences, DIMEC, University of Bologna, Bologna, Italy; Address for reprints: Luca Di Marco, MD, PhD, Division of Cardiac Surgery, Cardio-Thoraco-Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant’Orsola, Via Massarenti 9, Bologna, 40138, Italy.Cardiac Surgery Unit, Department of Medical and Surgical Sciences, DIMEC, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, ItalyPediatric and Adult CardioThoracic and Vascular, Oncohematologic and Emergency Radiology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, ItalyCardiac Surgery Unit, Department of Medical and Surgical Sciences, DIMEC, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, ItalyPediatric and Adult CardioThoracic and Vascular, Oncohematologic and Emergency Radiology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, ItalyCardiac Surgery Unit, Department of Medical and Surgical Sciences, DIMEC, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, ItalyPediatric and Adult CardioThoracic and Vascular, Oncohematologic and Emergency Radiology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, ItalyCardiac Surgery Unit, Department of Medical and Surgical Sciences, DIMEC, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Department of Medical and Surgical Sciences, DIMEC, University of Bologna, Bologna, ItalyObjectives: In the last few years, fenestrated, branched, or scalloped custom grafts have become available for aortic arch repair. Open surgery is the gold standard, but arch thoracic endovascular aortic repair (TEVAR) is indicated for high-risk patients. We focused on total endovascular aortic arch replacement with a zone 0 or zone 1 landing zone to describe its short- and long-term outcomes. Methods: We retrospectively analyzed patients who underwent arch TEVAR with a zone 0 or zone 1 landing zone at our center. We then performed a Kaplan-Meier analysis for survival and freedom from reintervention at follow-up. Results: From May 2017 to November 2023, 15 patients underwent elective arch TEVAR, having been deemed unfit for open surgery. Mean age was 74.7 ± 7.8 years. The most frequent procedure was fenestrated endovascular aortic repair with a left carotid-subclavian bypass (LCSB) (6; 40%), followed by double-branched graft with LCSB (5; 33.3%) and triple-branched graft (2; 13.3%) and scalloped graft with LCSB (2; 13.3%). There was 1 in-hospital death (6.7%). Perioperative stroke occurred in 2 cases (13.3%). Mean follow-up (FU) time was 16.4 ± 15.1 months. There were 3 deaths at FU, all for noncardiovascular causes, and 1 stroke at FU. One patient required further stenting of the brachiocephalic trunk for a type III endoleak. Survival at 12 months was 87.5% and freedom from reintervention was 85.7%. Conclusions: Total endovascular aortic arch repair with custom-made prosthesis is a safe and effective procedure in patients with prohibitive surgical risk. Stroke remains the main complication with significant rates.http://www.sciencedirect.com/science/article/pii/S2666250724003602endovascularaortic archstent graftsTEVARBEVARFEVAR
spellingShingle Luca Di Marco, MD, PhD
Chiara Nocera, MD, PhD
Francesco Buia, MD
Francesco Campanini, MD
Domenico Attinà, MD
Giacomo Murana, MD
Luigi Lovato, MD
Davide Pacini, MD, PhD
Total endovascular arch repair: Initial experience in BolognaCentral MessagePerspective
JTCVS Techniques
endovascular
aortic arch
stent grafts
TEVAR
BEVAR
FEVAR
title Total endovascular arch repair: Initial experience in BolognaCentral MessagePerspective
title_full Total endovascular arch repair: Initial experience in BolognaCentral MessagePerspective
title_fullStr Total endovascular arch repair: Initial experience in BolognaCentral MessagePerspective
title_full_unstemmed Total endovascular arch repair: Initial experience in BolognaCentral MessagePerspective
title_short Total endovascular arch repair: Initial experience in BolognaCentral MessagePerspective
title_sort total endovascular arch repair initial experience in bolognacentral messageperspective
topic endovascular
aortic arch
stent grafts
TEVAR
BEVAR
FEVAR
url http://www.sciencedirect.com/science/article/pii/S2666250724003602
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