Magnesium-related gene ITGAL: a key immunotherapy predictor and prognostic biomarker in pan-cancer

Magnesium-related gene ITGAL: a key immunotherapy predictor and prognostic biomarker in pan-cancer

BackgroundIntegrin subunit alpha L (ITGAL) is crucial for activating CD8+ T cells through magnesium-mediated immune synapse formation and specific cytotoxicity. ITGAL might exert an important function in the growth and transformation of cancer.MethodsOur study comprehensively analyzed ITGAL expressi...

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Bibliographic Details
Main Authors: Fengjie Lin, Hanxuan Yang, Zongwei Huang, Ying Li, Qin Ding, Yunbin Ye, Sufang Qiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Pharmacology
Subjects:
ITGAL
pan-cacner
immunothearpy
magnesium-related
HNSCC
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1464830/full
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