Is Preoperative Anemia a Prognostic Marker in Patients Who Underwent Pneumonectomy for Non-Small Cell Lung Cancer?
Objective: Pneumonectomy is infrequently selected for lung resections due to the high rate of postoperative complications. Thus, identifying risk factors for complications and predicting potential prognostic factors in patients undergoing pneumonectomy is of great importance. We have already describ...
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2024-08-01
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| Series: | Cerrahpaşa Medical Journal |
| Online Access: | https://cerrahpasamedj.org/en/is-preoperative-anemia-a-prognostic-marker-in-patients-who-underwent-pneumonectomy-for-non-small-cell-lung-cancer-131265 |
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| author | Burcu Kılıç Gizem Özçıbık Işık Tolunay Turan Ezel Erşen H. Volkan Kara M. Kamil Kaynak Akif Turna |
| author_facet | Burcu Kılıç Gizem Özçıbık Işık Tolunay Turan Ezel Erşen H. Volkan Kara M. Kamil Kaynak Akif Turna |
| author_sort | Burcu Kılıç |
| collection | DOAJ |
| description | Objective: Pneumonectomy is infrequently selected for lung resections due to the high rate of postoperative complications. Thus, identifying risk factors for complications and predicting potential prognostic factors in patients undergoing pneumonectomy is of great importance. We have already described anemia in preoperative patients as a risk factor for postoperative complications. Our objective was to investigate the impact of anemia on pneumonectomy patients’ postoperative course and reveal any potential prognostic effects.
Methods: In total, 118 patients who underwent pneumonectomy between 2001 and 2022 were retrospectively assessed. Clinical data, laboratory data, pulmonary function values, pathological data, and survival data were retrospectively recorded, and this data was divided into 2 groups: preoperative hemoglobin values (group 1 anemic: 51 patients) and normal hemogram values (group 2 normal: 67 patients). Univariate and multivariate analyses were conducted.
Results: The evaluation of the development of complications in patients who underwent pneumonectomy did not reveal any clinical condition to be a risk factor, apart from anemia. The Charlson comorbidity risk index, pulmonary risk index, and cardiac risk index were not risk factors for complications in pneumonectomy patients (P = .324, P = .192, P = .727, respectively). A significant difference in survival rates was observed between the groups with and without anemia (P = .028).
Conclusion: Anaemia was identified as the only prognostic factor in patients who underwent pneumonectomy. Clinical significance must be taken into account to ensure survival benefits. |
| format | Article |
| id | doaj-art-99bc7aeb99eb47708f63823815260ca1 |
| institution | Kabale University |
| issn | 2687-1904 |
| language | English |
| publishDate | 2024-08-01 |
| publisher | AVES |
| record_format | Article |
| series | Cerrahpaşa Medical Journal |
| spelling | doaj-art-99bc7aeb99eb47708f63823815260ca12024-12-05T16:14:46ZengAVESCerrahpaşa Medical Journal2687-19042024-08-0148215215810.5152/cjm.2024.24011Is Preoperative Anemia a Prognostic Marker in Patients Who Underwent Pneumonectomy for Non-Small Cell Lung Cancer?Burcu Kılıç0Gizem Özçıbık Işık 1Tolunay Turan 2Ezel Erşen 3H. Volkan Kara4M. Kamil Kaynak 5Akif Turna6Department of Thoracic Surgery, İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, İstanbul, TürkiyeDepartment of Thoracic Surgery, İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, İstanbul, TürkiyeDepartment of Thoracic Surgery, İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, İstanbul, TürkiyeDepartment of Thoracic Surgery, İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, İstanbul, TürkiyeDepartment of Thoracic Surgery, İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, İstanbul, TürkiyeDepartment of Thoracic Surgery, İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, İstanbul, TürkiyeDepartment of Thoracic Surgery, İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, İstanbul, TürkiyeObjective: Pneumonectomy is infrequently selected for lung resections due to the high rate of postoperative complications. Thus, identifying risk factors for complications and predicting potential prognostic factors in patients undergoing pneumonectomy is of great importance. We have already described anemia in preoperative patients as a risk factor for postoperative complications. Our objective was to investigate the impact of anemia on pneumonectomy patients’ postoperative course and reveal any potential prognostic effects. Methods: In total, 118 patients who underwent pneumonectomy between 2001 and 2022 were retrospectively assessed. Clinical data, laboratory data, pulmonary function values, pathological data, and survival data were retrospectively recorded, and this data was divided into 2 groups: preoperative hemoglobin values (group 1 anemic: 51 patients) and normal hemogram values (group 2 normal: 67 patients). Univariate and multivariate analyses were conducted. Results: The evaluation of the development of complications in patients who underwent pneumonectomy did not reveal any clinical condition to be a risk factor, apart from anemia. The Charlson comorbidity risk index, pulmonary risk index, and cardiac risk index were not risk factors for complications in pneumonectomy patients (P = .324, P = .192, P = .727, respectively). A significant difference in survival rates was observed between the groups with and without anemia (P = .028). Conclusion: Anaemia was identified as the only prognostic factor in patients who underwent pneumonectomy. Clinical significance must be taken into account to ensure survival benefits.https://cerrahpasamedj.org/en/is-preoperative-anemia-a-prognostic-marker-in-patients-who-underwent-pneumonectomy-for-non-small-cell-lung-cancer-131265 |
| spellingShingle | Burcu Kılıç Gizem Özçıbık Işık Tolunay Turan Ezel Erşen H. Volkan Kara M. Kamil Kaynak Akif Turna Is Preoperative Anemia a Prognostic Marker in Patients Who Underwent Pneumonectomy for Non-Small Cell Lung Cancer? Cerrahpaşa Medical Journal |
| title | Is Preoperative Anemia a Prognostic Marker in Patients Who Underwent Pneumonectomy for Non-Small Cell Lung Cancer? |
| title_full | Is Preoperative Anemia a Prognostic Marker in Patients Who Underwent Pneumonectomy for Non-Small Cell Lung Cancer? |
| title_fullStr | Is Preoperative Anemia a Prognostic Marker in Patients Who Underwent Pneumonectomy for Non-Small Cell Lung Cancer? |
| title_full_unstemmed | Is Preoperative Anemia a Prognostic Marker in Patients Who Underwent Pneumonectomy for Non-Small Cell Lung Cancer? |
| title_short | Is Preoperative Anemia a Prognostic Marker in Patients Who Underwent Pneumonectomy for Non-Small Cell Lung Cancer? |
| title_sort | is preoperative anemia a prognostic marker in patients who underwent pneumonectomy for non small cell lung cancer |
| url | https://cerrahpasamedj.org/en/is-preoperative-anemia-a-prognostic-marker-in-patients-who-underwent-pneumonectomy-for-non-small-cell-lung-cancer-131265 |
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