A novel muscle network approach for objective assessment and profiling of bulbar involvement in ALS

A novel muscle network approach for objective assessment and profiling of bulbar involvement in ALS

IntroductionAs a hallmark feature of amyotrophic lateral sclerosis (ALS), bulbar involvement significantly impacts psychosocial, emotional, and physical health. A validated objective marker is however lacking to characterize and phenotype bulbar involvement, positing a major barrier to early detecti...

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Bibliographic Details
Main Authors: Panying Rong, Lindsey Heidrick, Gary Pattee
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Neuroscience
Subjects:
graph neural networks
masticatory muscles
speech disorders
neurodegenerative diseases
amyotrophic lateral sclerosis
surface electromyography
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2024.1491997/full
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