New Germline TP53 Variant Detected After Radiotherapy-Induced Angiosarcoma of the Chest Wall in a Previously Treated Breast Cancer Patient: A Case Report and Review of Li–Fraumeni Syndrome and Radiotherapy-Induced Sarcoma

Li–Fraumeni syndrome (LFS) is one of the most common hereditary cancer predisposition syndromes in Brazil. The high frequency of the syndrome is due to a founding variant (R337H) in the country. LFS is characterized by a wide variety of malignant phenotypes. Despite the great epidemiological importa...

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Bibliographic Details
Main Authors: Bruna Bianca Lopes David, Sávio Solon Alves Silva, Vanessa Dinoa, Tadeu Diniz, Emilio Pereira, Carolina Bustamante, Bernardo Garicochea
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/crom/6640468
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