Development of a prognostic model based on lysosome-related genes for ovarian cancer: insights into tumor microenvironment, mutation patterns, and personalized treatment strategies

Development of a prognostic model based on lysosome-related genes for ovarian cancer: insights into tumor microenvironment, mutation patterns, and personalized treatment strategies

Abstract Background Ovarian cancer (OC) is often associated with an unfavorable prognosis. Given the crucial involvement of lysosomes in tumor advancement, lysosome-related genes (LRGs) hold promise as potential therapeutic targets. Methods To identify differentially expressed lysosome-related genes...

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Bibliographic Details
Main Authors: Ran Sun, Siyi Li, Wanlu Ye, Yanming Lu
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Cancer Cell International
Subjects:
Ovarian cancer
Lysosome
Prognosis
Tumor microenvironment
Risk signature
qRT-PCR
Online Access:https://doi.org/10.1186/s12935-024-03586-w
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