Green mycosynthesis of silver nanoparticles exhibiting antimalarial activity
In the present study, different parameters, affecting the growth of Thermomyces lanuginosus BJMDU1 and extracellular synthesis of silver nanoparticles (AgNPs), were studied. Culture extract of thermophilic mould Thermomyces lanuginosus BJMDU1 showed potential in green synthesis of silver nanoparticl...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-12-01
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| Series: | Journal of Taibah University for Science |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/16583655.2024.2381286 |
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| author | Akshay Shankar Naveen Kumar Kaushik Vinod Kumar Vinay Malik Davender Singh Vijay Kumar Bijender Singh |
| author_facet | Akshay Shankar Naveen Kumar Kaushik Vinod Kumar Vinay Malik Davender Singh Vijay Kumar Bijender Singh |
| author_sort | Akshay Shankar |
| collection | DOAJ |
| description | In the present study, different parameters, affecting the growth of Thermomyces lanuginosus BJMDU1 and extracellular synthesis of silver nanoparticles (AgNPs), were studied. Culture extract of thermophilic mould Thermomyces lanuginosus BJMDU1 showed potential in green synthesis of silver nanoparticles when the fungus was grown in a sucrose yeast extract medium (pH 8.0) at 45°C. Mycosynthesis of AgNPs was enhanced in the presence of light using 2 mM AgNO3 and 200 µl of culture extract at 50°C. The reaction parameters significantly improved the synthesis of AgNPs. Techniques like UV-Vis & FT-IR spectroscopy, X-ray diffraction, transmission electron microscopy and dynamic light scattering were used to characterise AgNPs. Biogenic nanoparticles showed an absorption peak at 430 nm having 80 nm size. Biogenic AgNPs showed potent antibacterial and antiplasmodial activity with no haemolysis up to 40 µg/ml. The p-nitrophenol was catalytically reduced to p-aminophenol by AgNPs. Therefore, green mycosynthesised AgNPs could be used in the therapeutics and remediation of environmental pollutants. |
| format | Article |
| id | doaj-art-9858ef8e640b45b785452c5d572fbbbd |
| institution | Kabale University |
| issn | 1658-3655 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Taibah University for Science |
| spelling | doaj-art-9858ef8e640b45b785452c5d572fbbbd2024-12-17T11:38:48ZengTaylor & Francis GroupJournal of Taibah University for Science1658-36552024-12-0118110.1080/16583655.2024.2381286Green mycosynthesis of silver nanoparticles exhibiting antimalarial activityAkshay Shankar0Naveen Kumar Kaushik1Vinod Kumar2Vinay Malik3Davender Singh4Vijay Kumar5Bijender Singh6Laboratory of Bioprocess Technology, Department of Microbiology, Maharshi Dayanand University, Rohtak, IndiaAmity Institute of Virology and Immunology, Amity University Uttar Pradesh, Noida, Uttar Pradesh, IndiaDepartment of Biotechnology, Central University of Haryana, Mahendergarh, IndiaDepartment of Zoology, Maharishi Dayanand University, Rohtak, IndiaDepartment of Physics, RPS Degree College, Mahendragarh, IndiaDepartment of Botany, Shivaji College, University of Delhi, New Delhi, IndiaLaboratory of Bioprocess Technology, Department of Microbiology, Maharshi Dayanand University, Rohtak, IndiaIn the present study, different parameters, affecting the growth of Thermomyces lanuginosus BJMDU1 and extracellular synthesis of silver nanoparticles (AgNPs), were studied. Culture extract of thermophilic mould Thermomyces lanuginosus BJMDU1 showed potential in green synthesis of silver nanoparticles when the fungus was grown in a sucrose yeast extract medium (pH 8.0) at 45°C. Mycosynthesis of AgNPs was enhanced in the presence of light using 2 mM AgNO3 and 200 µl of culture extract at 50°C. The reaction parameters significantly improved the synthesis of AgNPs. Techniques like UV-Vis & FT-IR spectroscopy, X-ray diffraction, transmission electron microscopy and dynamic light scattering were used to characterise AgNPs. Biogenic nanoparticles showed an absorption peak at 430 nm having 80 nm size. Biogenic AgNPs showed potent antibacterial and antiplasmodial activity with no haemolysis up to 40 µg/ml. The p-nitrophenol was catalytically reduced to p-aminophenol by AgNPs. Therefore, green mycosynthesised AgNPs could be used in the therapeutics and remediation of environmental pollutants.https://www.tandfonline.com/doi/10.1080/16583655.2024.2381286Thermomyces lanuginosus BJMDU1silver nanoparticlesculture filtratecatalysisantimalarial activity |
| spellingShingle | Akshay Shankar Naveen Kumar Kaushik Vinod Kumar Vinay Malik Davender Singh Vijay Kumar Bijender Singh Green mycosynthesis of silver nanoparticles exhibiting antimalarial activity Journal of Taibah University for Science Thermomyces lanuginosus BJMDU1 silver nanoparticles culture filtrate catalysis antimalarial activity |
| title | Green mycosynthesis of silver nanoparticles exhibiting antimalarial activity |
| title_full | Green mycosynthesis of silver nanoparticles exhibiting antimalarial activity |
| title_fullStr | Green mycosynthesis of silver nanoparticles exhibiting antimalarial activity |
| title_full_unstemmed | Green mycosynthesis of silver nanoparticles exhibiting antimalarial activity |
| title_short | Green mycosynthesis of silver nanoparticles exhibiting antimalarial activity |
| title_sort | green mycosynthesis of silver nanoparticles exhibiting antimalarial activity |
| topic | Thermomyces lanuginosus BJMDU1 silver nanoparticles culture filtrate catalysis antimalarial activity |
| url | https://www.tandfonline.com/doi/10.1080/16583655.2024.2381286 |
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