Congenital Melanocytic Naevi

ABSTRACT Congenital melanocytic naevi (CMN) are birthmarks that can cover large areas of the body. CMN can significantly impact individuals' lives due to perceived stigma, the risk for melanoma development and neurological complications. To treat and prevent these complications, adequate resear...

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Main Authors: A. C. Fledderus, C. J. A. vanEijsden, N. denHertog, M. S. vanKessel, A. Wolkerstorfer, M. M. Pleumeekers, S. G. M. A. Pasmans
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:JEADV Clinical Practice
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Online Access:https://doi.org/10.1002/jvc2.70079
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author A. C. Fledderus
C. J. A. vanEijsden
N. denHertog
M. S. vanKessel
A. Wolkerstorfer
M. M. Pleumeekers
S. G. M. A. Pasmans
author_facet A. C. Fledderus
C. J. A. vanEijsden
N. denHertog
M. S. vanKessel
A. Wolkerstorfer
M. M. Pleumeekers
S. G. M. A. Pasmans
author_sort A. C. Fledderus
collection DOAJ
description ABSTRACT Congenital melanocytic naevi (CMN) are birthmarks that can cover large areas of the body. CMN can significantly impact individuals' lives due to perceived stigma, the risk for melanoma development and neurological complications. To treat and prevent these complications, adequate research and guidelines are needed. In this review, we present a summary of the Dutch multidisciplinary guideline and the lessons learned from the implementation and information developed additionally in collaboration with the patient association. We also introduce the core outcomes of the OCOMEN project to standardize outcomes for both research and care of CMN. The next step is the development of the instruments internationally.
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spelling doaj-art-97e7bb75f7e541c6b3c74a626e8ffdae2025-08-20T04:02:17ZengWileyJEADV Clinical Practice2768-65662025-08-014369069610.1002/jvc2.70079Congenital Melanocytic NaeviA. C. Fledderus0C. J. A. vanEijsden1N. denHertog2M. S. vanKessel3A. Wolkerstorfer4M. M. Pleumeekers5S. G. M. A. Pasmans6Department of Dermatology, Center of Pediatric Dermatology Sophia Children's Hospital, Center of Rare Skin Diseases Erasmus MC University Medical Center Rotterdam‐Sophia Children's Hospital Rotterdam the NetherlandsDepartment of Dermatology, Center of Pediatric Dermatology Sophia Children's Hospital, Center of Rare Skin Diseases Erasmus MC University Medical Center Rotterdam‐Sophia Children's Hospital Rotterdam the NetherlandsDutch Multidisciplinary Congenital Nevus Network, ERN‐SKIN‐Subthematic group Mosaicism Paris FrancePatient Association Congenital Melanocytic Nevi: Nevus Netwerk Nederland Sivolde the NetherlandsDepartment of Dermatology Amsterdam University Medical Center Amsterdam, Dutch Multidisciplinary Congenital Nevus Network Amsterdam the NetherlandsDutch Multidisciplinary Congenital Nevus Network, ERN‐SKIN‐Subthematic group Mosaicism Paris FranceDepartment of Dermatology, Center of Pediatric Dermatology Sophia Children's Hospital, Center of Rare Skin Diseases Erasmus MC University Medical Center Rotterdam‐Sophia Children's Hospital Rotterdam the NetherlandsABSTRACT Congenital melanocytic naevi (CMN) are birthmarks that can cover large areas of the body. CMN can significantly impact individuals' lives due to perceived stigma, the risk for melanoma development and neurological complications. To treat and prevent these complications, adequate research and guidelines are needed. In this review, we present a summary of the Dutch multidisciplinary guideline and the lessons learned from the implementation and information developed additionally in collaboration with the patient association. We also introduce the core outcomes of the OCOMEN project to standardize outcomes for both research and care of CMN. The next step is the development of the instruments internationally.https://doi.org/10.1002/jvc2.70079congenital nevicore‐outcome‐setguidelinemelanomaneurocutaneous melanosispatient information
spellingShingle A. C. Fledderus
C. J. A. vanEijsden
N. denHertog
M. S. vanKessel
A. Wolkerstorfer
M. M. Pleumeekers
S. G. M. A. Pasmans
Congenital Melanocytic Naevi
JEADV Clinical Practice
congenital nevi
core‐outcome‐set
guideline
melanoma
neurocutaneous melanosis
patient information
title Congenital Melanocytic Naevi
title_full Congenital Melanocytic Naevi
title_fullStr Congenital Melanocytic Naevi
title_full_unstemmed Congenital Melanocytic Naevi
title_short Congenital Melanocytic Naevi
title_sort congenital melanocytic naevi
topic congenital nevi
core‐outcome‐set
guideline
melanoma
neurocutaneous melanosis
patient information
url https://doi.org/10.1002/jvc2.70079
work_keys_str_mv AT acfledderus congenitalmelanocyticnaevi
AT cjavaneijsden congenitalmelanocyticnaevi
AT ndenhertog congenitalmelanocyticnaevi
AT msvankessel congenitalmelanocyticnaevi
AT awolkerstorfer congenitalmelanocyticnaevi
AT mmpleumeekers congenitalmelanocyticnaevi
AT sgmapasmans congenitalmelanocyticnaevi