A phosphorylation switch in the Mediator MED15 controls cellular senescence and cognitive decline
Abstract A hallmark of aging is chronic systemic inflammation, which is exacerbated by the hypersecretory aging phenotype known as the senescence-associated secretory phenotype (SASP). How the SASP is initiated to accelerate tissue inflammation and aging is an outstanding question in aging biology....
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-08-01
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| Series: | Cell Discovery |
| Online Access: | https://doi.org/10.1038/s41421-025-00820-1 |
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