Combination therapy versus monotherapy: retrospective analysis of antibiotic treatment of enterococcal endocarditis

Combination therapy versus monotherapy: retrospective analysis of antibiotic treatment of enterococcal endocarditis

Abstract Background Guidelines suggest treating fully penicillin-susceptible Enterococcus faecalis strains causing infective endocarditis with amoxicillin combined with gentamicin or ceftriaxone, but clinical evidence to support this practice is limited and monotherapy cohorts were excluded from stu...

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Bibliographic Details
Main Authors: Razan Saman, Christopher P. Primus, Robert West, Simon J. Woldman, Jonathan A. T. Sandoe
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Infectious Diseases
Subjects:
Enterococcus faecalis
Infective endocarditis
Biofilm
Gentamicin
Amoxicillin
Online Access:https://doi.org/10.1186/s12879-025-10451-2
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