Functional properties of dietary quercetin in cardiovascular health and disease
Abstract The increasing incidence of cardiovascular diseases has resulted in an escalating need for natural dietary supplements with cardioprotective properties. This review provides a thorough analysis of laboratory and clinical studies conducted on dietary quercetin, a widely available flavonoid,...
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| Format: | Article |
| Language: | English |
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Wiley
2024-09-01
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| Series: | Food Frontiers |
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| Online Access: | https://doi.org/10.1002/fft2.434 |
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| author | Kuo Xu Liqun Qu Hui Li Xia Ren Ning Yan Xianjun Fu |
| author_facet | Kuo Xu Liqun Qu Hui Li Xia Ren Ning Yan Xianjun Fu |
| author_sort | Kuo Xu |
| collection | DOAJ |
| description | Abstract The increasing incidence of cardiovascular diseases has resulted in an escalating need for natural dietary supplements with cardioprotective properties. This review provides a thorough analysis of laboratory and clinical studies conducted on dietary quercetin, a widely available flavonoid, and its influence on the management of cardiovascular health and disease. The references cited in this review were obtained from reputable databases, including SciFinder, Web of Science, and ClinicalTrials.gov, with a specific focus on the period spanning from 1999 to 2023 pertaining to this subject matter. Notably, a bibliometric approach was used to analyze the bibliometric attribute trends of the research on quercetin associated with vascular health for the first time. Numerous investigations conducted on animal and human subjects at different phases of cardiac illness have consistently shown that the administration of quercetin substances improves cardiac function, suggesting the potential efficacy of quercetin in the management of heart disease. Evidently, the consumption of quercetin through dietary sources holds promise in conferring significant cardiovascular benefits through physiological mechanisms and biochemical signaling pathways, thus positioning it as a promising dietary contender for the prevention of cardiovascular disorders. Renewable food resources, including lovage leaves, elderberry, and radish leaves, which are abundant in quercetin, exhibit significant potential for the development and production of novel healthcare products with the objective of preventing cardiovascular disorders. This review is anticipated to provide valuable insights for the advancement of cardioprotective functional foods in the foreseeable future. |
| format | Article |
| id | doaj-art-971e45ecfeb6478c986f94b2f8eda5bb |
| institution | Kabale University |
| issn | 2643-8429 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Food Frontiers |
| spelling | doaj-art-971e45ecfeb6478c986f94b2f8eda5bb2024-11-17T09:43:58ZengWileyFood Frontiers2643-84292024-09-01551951196710.1002/fft2.434Functional properties of dietary quercetin in cardiovascular health and diseaseKuo Xu0Liqun Qu1Hui Li2Xia Ren3Ning Yan4Xianjun Fu5Research Institute for Marine Traditional Chinese Medicine, The SATCM's Key Unit of Discovering and Developing New Marine TCM Drugs, Key Laboratory of Marine Traditional Chinese Medicine in Shandong Universities, Shandong Engineering and Technology Research Center on Omics of Traditional Chinese Medicine Shandong University of Traditional Chinese Medicine Jinan ChinaResearch Institute for Marine Traditional Chinese Medicine, The SATCM's Key Unit of Discovering and Developing New Marine TCM Drugs, Key Laboratory of Marine Traditional Chinese Medicine in Shandong Universities, Shandong Engineering and Technology Research Center on Omics of Traditional Chinese Medicine Shandong University of Traditional Chinese Medicine Jinan ChinaResearch Institute for Marine Traditional Chinese Medicine, The SATCM's Key Unit of Discovering and Developing New Marine TCM Drugs, Key Laboratory of Marine Traditional Chinese Medicine in Shandong Universities, Shandong Engineering and Technology Research Center on Omics of Traditional Chinese Medicine Shandong University of Traditional Chinese Medicine Jinan ChinaResearch Institute for Marine Traditional Chinese Medicine, The SATCM's Key Unit of Discovering and Developing New Marine TCM Drugs, Key Laboratory of Marine Traditional Chinese Medicine in Shandong Universities, Shandong Engineering and Technology Research Center on Omics of Traditional Chinese Medicine Shandong University of Traditional Chinese Medicine Jinan ChinaPlant Functional Component Research Center Tobacco Research Institute of Chinese Academy of Agricultural Sciences Qingdao ChinaResearch Institute for Marine Traditional Chinese Medicine, The SATCM's Key Unit of Discovering and Developing New Marine TCM Drugs, Key Laboratory of Marine Traditional Chinese Medicine in Shandong Universities, Shandong Engineering and Technology Research Center on Omics of Traditional Chinese Medicine Shandong University of Traditional Chinese Medicine Jinan ChinaAbstract The increasing incidence of cardiovascular diseases has resulted in an escalating need for natural dietary supplements with cardioprotective properties. This review provides a thorough analysis of laboratory and clinical studies conducted on dietary quercetin, a widely available flavonoid, and its influence on the management of cardiovascular health and disease. The references cited in this review were obtained from reputable databases, including SciFinder, Web of Science, and ClinicalTrials.gov, with a specific focus on the period spanning from 1999 to 2023 pertaining to this subject matter. Notably, a bibliometric approach was used to analyze the bibliometric attribute trends of the research on quercetin associated with vascular health for the first time. Numerous investigations conducted on animal and human subjects at different phases of cardiac illness have consistently shown that the administration of quercetin substances improves cardiac function, suggesting the potential efficacy of quercetin in the management of heart disease. Evidently, the consumption of quercetin through dietary sources holds promise in conferring significant cardiovascular benefits through physiological mechanisms and biochemical signaling pathways, thus positioning it as a promising dietary contender for the prevention of cardiovascular disorders. Renewable food resources, including lovage leaves, elderberry, and radish leaves, which are abundant in quercetin, exhibit significant potential for the development and production of novel healthcare products with the objective of preventing cardiovascular disorders. This review is anticipated to provide valuable insights for the advancement of cardioprotective functional foods in the foreseeable future.https://doi.org/10.1002/fft2.434cardiovasculardietary supplementflavonoidquercetin |
| spellingShingle | Kuo Xu Liqun Qu Hui Li Xia Ren Ning Yan Xianjun Fu Functional properties of dietary quercetin in cardiovascular health and disease Food Frontiers cardiovascular dietary supplement flavonoid quercetin |
| title | Functional properties of dietary quercetin in cardiovascular health and disease |
| title_full | Functional properties of dietary quercetin in cardiovascular health and disease |
| title_fullStr | Functional properties of dietary quercetin in cardiovascular health and disease |
| title_full_unstemmed | Functional properties of dietary quercetin in cardiovascular health and disease |
| title_short | Functional properties of dietary quercetin in cardiovascular health and disease |
| title_sort | functional properties of dietary quercetin in cardiovascular health and disease |
| topic | cardiovascular dietary supplement flavonoid quercetin |
| url | https://doi.org/10.1002/fft2.434 |
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